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2020 1
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2023 1
2024 0

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Page 1
TAL1 activation in T-cell acute lymphoblastic leukemia: a novel oncogenic 3' neo-enhancer.
Smith C, Goyal A, Weichenhan D, Allemand E, Mayakonda A, Toprak U, Riedel A, Balducci E, Manojkumar M, Pejkovska A, Mücke O, Sollier E, Bakr A, Breuer K, Lutsik P, Hermine O, Spicuglia S, Asnafi V, Plass C, Touzart A. Smith C, et al. Among authors: breuer k. Haematologica. 2023 May 1;108(5):1259-1271. doi: 10.3324/haematol.2022.281583. Haematologica. 2023. PMID: 36632736 Free PMC article.
Histone H3K27 demethylase KDM6A is an epigenetic gatekeeper of mTORC1 signalling in cancer.
Revia S, Seretny A, Wendler L, Banito A, Eckert C, Breuer K, Mayakonda A, Lutsik P, Evert M, Ribback S, Gallage S, Chikh Bakri I, Breuhahn K, Schirmacher P, Heinrich S, Gaida MM, Heikenwälder M, Calvisi DF, Plass C, Lowe SW, Tschaharganeh DF. Revia S, et al. Among authors: breuer k. Gut. 2022 Aug;71(8):1613-1628. doi: 10.1136/gutjnl-2021-325405. Epub 2021 Sep 11. Gut. 2022. PMID: 34509979 Free PMC article.
The age of the bone marrow microenvironment influences B-cell acute lymphoblastic leukemia progression via CXCR5-CXCL13.
Zanetti C, Kumar R, Ender J, Godavarthy PS, Hartmann M, Hey J, Breuer K, Weissenberger ES, Minciacchi VR, Karantanou C, Gu Z, Roberts KG, Metzler M, Stock W, Mullighan CG, Bloomfield CD, Filmann N, Bankov K, Hartmann S, Hasserjian RP, Cousins AF, Halsey C, Plass C, Lipka DB, Krause DS. Zanetti C, et al. Among authors: breuer k. Blood. 2021 Nov 11;138(19):1870-1884. doi: 10.1182/blood.2021011557. Blood. 2021. PMID: 34424946 Free PMC article.
Epigenetic Modulation of Radiation-Induced Diacylglycerol Kinase Alpha Expression Prevents Pro-Fibrotic Fibroblast Response.
Liu CS, Toth R, Bakr A, Goyal A, Islam MS, Breuer K, Mayakonda A, Lin YY, Stepper P, Jurkowski TP, Veldwijk MR, Sperk E, Herskind C, Lutsik P, Weichenhan D, Plass C, Schmezer P, Popanda O. Liu CS, et al. Among authors: breuer k. Cancers (Basel). 2021 May 18;13(10):2455. doi: 10.3390/cancers13102455. Cancers (Basel). 2021. PMID: 34070078 Free PMC article.
Globally altered epigenetic landscape and delayed osteogenic differentiation in H3.3-G34W-mutant giant cell tumor of bone.
Lutsik P, Baude A, Mancarella D, Öz S, Kühn A, Toth R, Hey J, Toprak UH, Lim J, Nguyen VH, Jiang C, Mayakonda A, Hartmann M, Rosemann F, Breuer K, Vonficht D, Grünschläger F, Lee S, Schuhmacher MK, Kusevic D, Jauch A, Weichenhan D, Zustin J, Schlesner M, Haas S, Park JH, Park YJ, Oppermann U, Jeltsch A, Haller F, Fellenberg J, Lindroth AM, Plass C. Lutsik P, et al. Among authors: breuer k. Nat Commun. 2020 Oct 27;11(1):5414. doi: 10.1038/s41467-020-18955-y. Nat Commun. 2020. PMID: 33110075 Free PMC article.
ID3 promotes homologous recombination via non-transcriptional and transcriptional mechanisms and its loss confers sensitivity to PARP inhibition.
Bakr A, Hey J, Sigismondo G, Liu CS, Sadik A, Goyal A, Cross A, Iyer RL, Müller P, Trauernicht M, Breuer K, Lutsik P, Opitz CA, Krijgsveld J, Weichenhan D, Plass C, Popanda O, Schmezer P. Bakr A, et al. Among authors: breuer k. Nucleic Acids Res. 2021 Nov 18;49(20):11666-11689. doi: 10.1093/nar/gkab964. Nucleic Acids Res. 2021. PMID: 34718742 Free PMC article.