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1956 1
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1997 1
1998 1
1999 1
2002 2
2003 2
2004 2
2005 1
2006 3
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2012 3
2013 2
2015 3
2016 3
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Page 1
Whole-genome sequencing reveals host factors underlying critical COVID-19.
Kousathanas A, Pairo-Castineira E, Rawlik K, Stuckey A, Odhams CA, Walker S, Russell CD, Malinauskas T, Wu Y, Millar J, Shen X, Elliott KS, Griffiths F, Oosthuyzen W, Morrice K, Keating S, Wang B, Rhodes D, Klaric L, Zechner M, Parkinson N, Siddiq A, Goddard P, Donovan S, Maslove D, Nichol A, Semple MG, Zainy T, Maleady-Crowe F, Todd L, Salehi S, Knight J, Elgar G, Chan G, Arumugam P, Patch C, Rendon A, Bentley D, Kingsley C, Kosmicki JA, Horowitz JE, Baras A, Abecasis GR, Ferreira MAR, Justice A, Mirshahi T, Oetjens M, Rader DJ, Ritchie MD, Verma A, Fowler TA, Shankar-Hari M, Summers C, Hinds C, Horby P, Ling L, McAuley D, Montgomery H, Openshaw PJM, Elliott P, Walsh T, Tenesa A; GenOMICC investigators; 23andMe investigators; COVID-19 Human Genetics Initiative; Fawkes A, Murphy L, Rowan K, Ponting CP, Vitart V, Wilson JF, Yang J, Bretherick AD, Scott RH, Hendry SC, Moutsianas L, Law A, Caulfield MJ, Baillie JK. Kousathanas A, et al. Nature. 2022 Jul;607(7917):97-103. doi: 10.1038/s41586-022-04576-6. Epub 2022 Mar 7. Nature. 2022. PMID: 35255492 Free PMC article.
Immunonutrition.
Keith ME, Jeejeebhoy KN. Keith ME, et al. Baillieres Clin Endocrinol Metab. 1997 Dec;11(4):709-38. doi: 10.1016/s0950-351x(97)80990-1. Baillieres Clin Endocrinol Metab. 1997. PMID: 9589779 Review.
The immune system can be influenced by protein-energy malnutrition (PEM) and by catabolic illnesses such as sepsis and trauma, which in turn cause PEM. Specific trace element and vitamin deficiencies can also alter the immune state. ...
The immune system can be influenced by protein-energy malnutrition (PEM) and by catabolic illnesses such as sepsis and trauma, which in turn …
CRISPR-induced DNA reorganization for multiplexed nucleic acid detection.
Karlikow M, Amalfitano E, Yang X, Doucet J, Chapman A, Mousavi PS, Homme P, Sutyrina P, Chan W, Lemak S, Yakunin AF, Dolezal AG, Kelley S, Foster LJ, Harpur BA, Pardee K. Karlikow M, et al. Nat Commun. 2023 Mar 17;14(1):1505. doi: 10.1038/s41467-023-36874-6. Nat Commun. 2023. PMID: 36932065 Free PMC article.
While exciting, there are still many challenges facing their practical implementation, such as the widespread need for a PAM sequence in the targeted nucleic acid, labile RNA inputs, and limited multiplexing. Here we report FACT (Functionalized Amplification CRISPR Tracing …
While exciting, there are still many challenges facing their practical implementation, such as the widespread need for a PAM sequence in the …
Aerospace Pressure Effects.
Tarver WJ, Volner K, Cooper JS. Tarver WJ, et al. 2022 Oct 24. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. 2022 Oct 24. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 29262037 Free Books & Documents.
This concept is important given that the air humans breathe is a mixed gas of nitrogen (approximately 78%), oxygen (approximately 21%), and trace other gases. If the human body is exposed to a low enough absolute pressure, then surface fluids (tear film, saliva, and the ai …
This concept is important given that the air humans breathe is a mixed gas of nitrogen (approximately 78%), oxygen (approximately 21%), and …
Absent expansion of AXIN2+ hepatocytes and altered physiology in Axin2CreERT2 mice challenges the role of pericentral hepatocytes in homeostatic liver regeneration.
May S, Müller M, Livingstone CR, Skalka GL, Walsh PJ, Nixon C, Hedley A, Shaw R, Clark W, Vande Voorde J, Officer-Jones L, Ballantyne F, Powley IR, Drake TM, Kiourtis C, Keith A, Rocha AS, Tardito S, Sumpton D, Le Quesne J, Bushell M, Sansom OJ, Bird TG. May S, et al. J Hepatol. 2023 May;78(5):1028-1036. doi: 10.1016/j.jhep.2023.01.009. Epub 2023 Jan 23. J Hepatol. 2023. PMID: 36702176 Free article.
BACKGROUND & AIMS: Mouse models of lineage tracing have helped to describe the important subpopulations of hepatocytes responsible for liver regeneration. ...Herein, we aimed to reconcile these conflicting reports by repeating a key lineage-tracing study from pe …
BACKGROUND & AIMS: Mouse models of lineage tracing have helped to describe the important subpopulations of hepatocytes responsibl …
The first intravenous anaesthetic: how well was it managed and its potential realized?
Dorrington KL, Poole W. Dorrington KL, et al. Br J Anaesth. 2013 Jan;110(1):7-12. doi: 10.1093/bja/aes388. Epub 2012 Nov 15. Br J Anaesth. 2013. PMID: 23161361 Free article. Review.
Our speciality commonly traces its origin to a demonstration of the inhalation of ether by a patient undergoing surgery in Boston in 1846. ...
Our speciality commonly traces its origin to a demonstration of the inhalation of ether by a patient undergoing surgery in Boston in …
Molecular recognition of an aversive odorant by the murine trace amine-associated receptor TAAR7f.
Gusach A, Lee Y, Khoshgrudi AN, Mukhaleva E, Ma N, Koers EJ, Chen Q, Edwards PC, Huang F, Kim J, Mancia F, Verprintsev DB, Vaidehi N, Weyand SN, Tate CG. Gusach A, et al. bioRxiv [Preprint]. 2023 Jul 7:2023.07.07.547762. doi: 10.1101/2023.07.07.547762. bioRxiv. 2023. PMID: 37461561 Free PMC article. Preprint.
There are two main families of G protein-coupled receptors that detect odours in humans, the odorant receptors (ORs) and the trace amine-associated receptors (TAARs). Their amino acid sequences are distinct, with the TAARs being most similar to the aminergic receptors such …
There are two main families of G protein-coupled receptors that detect odours in humans, the odorant receptors (ORs) and the trace am …
The morphology of the cardiac conduction system.
Anderson RH, Ho SY. Anderson RH, et al. Novartis Found Symp. 2003;250:6-17; discussion 18-24, 276-9. Novartis Found Symp. 2003. PMID: 12956321 Review.
Thus, it was Tawara (in 1906) who clarified the arrangement of the specialized muscular axis responsible for atrioventricular conduction, while Keith & Flack (in 1907) published the first account of the sinus node. ...Such pathways should be composed of cells which are …
Thus, it was Tawara (in 1906) who clarified the arrangement of the specialized muscular axis responsible for atrioventricular conduction, wh …
ADAM "sequence" part II: hypothesis and speculation.
Opitz JM, Johnson DR, Gilbert-Barness EF. Opitz JM, et al. Am J Med Genet A. 2015 Mar;167A(3):478-503. doi: 10.1002/ajmg.a.36937. Epub 2015 Jan 21. Am J Med Genet A. 2015. PMID: 25604972 Review.
He concluded that an amniotic cord was "not an adhesion or inflammatory product but an anomalous developmental structure and present from the outset." In survivors the "traces" of damaged limb-buds "reveal the scars of poor germ-plasm." In 1958, Willis, in dismissing the a …
He concluded that an amniotic cord was "not an adhesion or inflammatory product but an anomalous developmental structure and present from th …
Unmasking pipefish otolith using synchrotron-based scanning X-ray fluorescence.
Haÿ V, Berland S, Medjoubi K, Somogyi A, Mennesson MI, Keith P, Lord C. Haÿ V, et al. Sci Rep. 2023 Mar 23;13(1):4794. doi: 10.1038/s41598-023-31798-z. Sci Rep. 2023. PMID: 36959216 Free PMC article.
Scientists use otoliths to trace fish life history, especially fish migrations. Otoliths incorporate signatures of individual growth and environmental use. ...
Scientists use otoliths to trace fish life history, especially fish migrations. Otoliths incorporate signatures of individual growth …
51 results