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Year Number of Results
1975 1
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1982 26
1983 19
1984 19
1985 25
1986 14
1987 33
1988 38
1989 42
1990 39
1991 36
1992 54
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1995 45
1996 61
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1998 52
1999 64
2000 69
2001 68
2002 74
2003 72
2004 112
2005 101
2006 109
2007 113
2008 107
2009 107
2010 101
2011 126
2012 131
2013 112
2014 120
2015 136
2016 50
2017 41
2018 53
2019 75
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2022 65
2023 58
2024 6

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The following term was not found in PubMed: Keani
Page 1
The intestinal MUC2 mucin C-terminus is stabilized by an extra disulfide bond in comparison to von Willebrand factor and other gel-forming mucins.
Gallego P, Garcia-Bonete MJ, Trillo-Muyo S, Recktenwald CV, Johansson MEV, Hansson GC. Gallego P, et al. Nat Commun. 2023 Apr 8;14(1):1969. doi: 10.1038/s41467-023-37666-8. Nat Commun. 2023. PMID: 37031240 Free PMC article.
The MUC2 mucin polymer is the main building unit of the intestinal mucus layers separating intestinal microbiota from the host epithelium. The MUC2 mucin is a large glycoprotein with a C-terminal domain similar to the MUC5AC and MUC5B mucins and the von Willebrand f …
The MUC2 mucin polymer is the main building unit of the intestinal mucus layers separating intestinal microbiota from the host epithelium. T …
Thrombotic Regulation From the Endothelial Cell Perspectives.
Wang M, Hao H, Leeper NJ, Zhu L; Early Career Committee. Wang M, et al. Arterioscler Thromb Vasc Biol. 2018 Jun;38(6):e90-e95. doi: 10.1161/ATVBAHA.118.310367. Arterioscler Thromb Vasc Biol. 2018. PMID: 29793992 Free PMC article. Review. No abstract available.
Thromboinflammation in Stroke Brain Damage.
De Meyer SF, Denorme F, Langhauser F, Geuss E, Fluri F, Kleinschnitz C. De Meyer SF, et al. Stroke. 2016 Apr;47(4):1165-72. doi: 10.1161/STROKEAHA.115.011238. Epub 2016 Jan 19. Stroke. 2016. PMID: 26786115 Review. No abstract available.
An apparently silent nucleotide substitution (c.7056C>T) in the von Willebrand factor gene is responsible for type 1 von Willebrand disease.
Daidone V, Gallinaro L, Grazia Cattini M, Pontara E, Bertomoro A, Pagnan A, Casonato A. Daidone V, et al. Haematologica. 2011 Jun;96(6):881-7. doi: 10.3324/haematol.2010.036848. Epub 2011 Mar 10. Haematologica. 2011. PMID: 21393328 Free PMC article.
DESIGN AND METHODS: We report an altered splicing process induced by a silent substitution (c.7056C>T) in the von Willebrand factor gene in a case of type 1 von Willebrand disease originally classified as lacking von Willebrand factor mutations. ... …
DESIGN AND METHODS: We report an altered splicing process induced by a silent substitution (c.7056C>T) in the von Willebrand …
von Willebrand factor clearance - biological mechanisms and clinical significance.
O'Sullivan JM, Ward S, Lavin M, O'Donnell JS. O'Sullivan JM, et al. Br J Haematol. 2018 Oct;183(2):185-195. doi: 10.1111/bjh.15565. Br J Haematol. 2018. PMID: 30378120 Free article. Review.
The mechanisms involved in regulating von Willebrand factor (VWF) clearance remain poorly understood. However recent studies have shown that macrophages play a critical role in regulating the half-life of VWF, and have identified specific lectin (including asialoglycoprote …
The mechanisms involved in regulating von Willebrand factor (VWF) clearance remain poorly understood. However recent studies have sho …
A new case of platelet-type von Willebrand disease supports the recent findings of gain-of-function GP1BA variants outside the C-terminal disulphide loop enhances affinity for von Willebrand factor.
Monteiro C, Gonçalves A, Pereira M, Lau C, Morais S, Santos R. Monteiro C, et al. Br J Haematol. 2023 Nov;203(4):673-677. doi: 10.1111/bjh.19025. Epub 2023 Aug 17. Br J Haematol. 2023. PMID: 37592722
Platelet-type von Willebrand disease (PT-VWD) is a rare autosomal dominant bleeding disorder characterized by an increased ristocetin-induced platelet aggregation (RIPA) and enhanced affinity of platelet glycoprotein Ibalpha (GPIbalpha) to von Willebrand factor (VWF …
Platelet-type von Willebrand disease (PT-VWD) is a rare autosomal dominant bleeding disorder characterized by an increased ristocetin …
Protein kinase C signaling dysfunction in von Willebrand disease (p.V1316M) type 2B platelets.
Casari C, Paul DS, Susen S, Lavenu-Bombled C, Harroche A, Piatt R, Poe KO, Lee RH, Bryckaert M, Christophe OD, Lenting PJ, Denis CV, Bergmeier W. Casari C, et al. Blood Adv. 2018 Jun 26;2(12):1417-1428. doi: 10.1182/bloodadvances.2017014290. Blood Adv. 2018. PMID: 29925524 Free PMC article.
von Willebrand disease (VWD) type 2B is characterized by gain-of-function mutations in von Willebrand factor (VWF), enhancing its binding affinity for the platelet receptor glycoprotein (GP)Ibalpha. ...Two distinct pathways contribute to Rap1 activation in platelets …
von Willebrand disease (VWD) type 2B is characterized by gain-of-function mutations in von Willebrand factor (VWF), enhancing …
PAD4 and von Willebrand Factor Link Inflammation and Thrombosis.
Morrell CN, Hilt ZT, Pariser DN, Maurya P. Morrell CN, et al. Circ Res. 2019 Aug 16;125(5):520-522. doi: 10.1161/CIRCRESAHA.119.315601. Epub 2019 Aug 15. Circ Res. 2019. PMID: 31415230 Free PMC article. No abstract available.
Replacement Therapy in Patients with Von Willebrand Disease-Indications and Monitoring.
Nowak-Göttl U, Miesbach W, Koscielny J, Dempfle CE, Maegele M, Prondzinski MVD, Westrup D, Spannagl M. Nowak-Göttl U, et al. Hamostaseologie. 2019 Nov;39(4):326-338. doi: 10.1055/s-0039-1692688. Epub 2019 Jul 30. Hamostaseologie. 2019. PMID: 31364093 Review. English.
The deficient von Willebrand factor (VWF) is replaced with or without factor VIII (FVIII). Dual VWF/FVIII concentrates can be beneficial in the case of low FVIII level, while repeated dosing may lead to very high FVIII levels, with a potential thrombogenic effect in indivi …
The deficient von Willebrand factor (VWF) is replaced with or without factor VIII (FVIII). Dual VWF/FVIII concentrates can be benefic …
Management of bleeding disorders in adults.
Peyvandi F, Klamroth R, Carcao M, Federici AB, DI Minno G, Jiménez-Yuste V, Rodriguez Merchán EC. Peyvandi F, et al. Haemophilia. 2012 May;18 Suppl 2:24-36. doi: 10.1111/j.1365-2516.2012.02797.x. Haemophilia. 2012. PMID: 22530576 Review.
In this section we will review some important aspects of the management of haemophilia in adults, including an overview of bleeding in women with von Willebrand disease, an analysis of FVIII consumption in patients with severe haemophilia A, an update of the ongoing RES.I. …
In this section we will review some important aspects of the management of haemophilia in adults, including an overview of bleeding in women …
2,645 results