Cross-coupling reaction with lithium methyltriolborate

Molecules. 2012 Dec 28;18(1):430-9. doi: 10.3390/molecules18010430.

Abstract

We newly developed lithium methyltriolborate as an air-stable white solid that is convenient to handle. The good performance of this triolborate for metal-catalyzed bond-forming reactions was demonstrated in palladium-catalyzed cross-coupling reactions with haloarenes. Cross-coupling reaction of [MeB(OCH₂)₃CCH₃]Li with aryl halides occurred in the presence of Pd(OAc)₂/RuPhos complex in refluxing MeOH/H₂O and the absence of bases.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Catalysis
  • Lithium / analysis
  • Lithium / metabolism*
  • Magnetic Resonance Spectroscopy
  • Methylation
  • Palladium / metabolism

Substances

  • Palladium
  • Lithium