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The translocator protein (TSPO) is prodromal to mitophagy loss in neurotoxicity.
Frison M, Faccenda D, Abeti R, Rigon M, Strobbe D, England-Rendon BS, Cash D, Barnes K, Sadeghian M, Sajic M, Wells LA, Xia D, Giunti P, Smith K, Mortiboys H, Turkheimer FE, Campanella M. Frison M, et al. Among authors: barnes k. Mol Psychiatry. 2021 Jul;26(7):2721-2739. doi: 10.1038/s41380-021-01050-z. Epub 2021 Mar 4. Mol Psychiatry. 2021. PMID: 33664474 Free PMC article.
Ursodeoxycholic Acid Improves Mitochondrial Function and Redistributes Drp1 in Fibroblasts from Patients with Either Sporadic or Familial Alzheimer's Disease.
Bell SM, Barnes K, Clemmens H, Al-Rafiah AR, Al-Ofi EA, Leech V, Bandmann O, Shaw PJ, Blackburn DJ, Ferraiuolo L, Mortiboys H. Bell SM, et al. Among authors: barnes k. J Mol Biol. 2018 Oct 19;430(21):3942-3953. doi: 10.1016/j.jmb.2018.08.019. Epub 2018 Aug 29. J Mol Biol. 2018. PMID: 30171839 Free PMC article.