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PD-1 checkpoint inhibition enhances the antilymphoma activity of CD19-CAR-iNKT cells that retain their ability to prevent alloreactivity.
Moraes Ribeiro E, Secker KA, Nitulescu AM, Schairer R, Keppeler H, Wesle A, Schmid H, Schmitt A, Neuber B, Chmiest D, Podavini S, Märklin M, Klimovich B, Schmitt M, Korkmaz F, Lengerke C, Schneidawind C, Schneidawind D. Moraes Ribeiro E, et al. Among authors: secker ka. J Immunother Cancer. 2024 Jan 31;12(1):e007829. doi: 10.1136/jitc-2023-007829. J Immunother Cancer. 2024. PMID: 38296597 Free PMC article.
Inhibition of effector B cells by ibrutinib in systemic sclerosis.
Einhaus J, Pecher AC, Asteriti E, Schmid H, Secker KA, Duerr-Stoerzer S, Keppeler H, Klein R, Schneidawind C, Henes J, Schneidawind D. Einhaus J, et al. Among authors: secker ka. Arthritis Res Ther. 2020 Mar 30;22(1):66. doi: 10.1186/s13075-020-02153-8. Arthritis Res Ther. 2020. PMID: 32228672 Free PMC article.
MAT2A as Key Regulator and Therapeutic Target in MLLr Leukemogenesis.
Secker KA, Bloechl B, Keppeler H, Duerr-Stoerzer S, Schmid H, Schneidawind D, Jeong J, Hentrich T, Schulze-Hentrich JM, Schneidawind C. Secker KA, et al. Cancers (Basel). 2020 May 24;12(5):1342. doi: 10.3390/cancers12051342. Cancers (Basel). 2020. PMID: 32456310 Free PMC article.
Invariant NKT Cells From Donor Lymphocyte Infusions (DLI-iNKTs) Promote ex vivo Lysis of Leukemic Blasts in a CD1d-Dependent Manner.
Jahnke S, Schmid H, Secker KA, Einhaus J, Duerr-Stoerzer S, Keppeler H, Schober-Melms I, Baur R, Schumm M, Handgretinger R, Bethge W, Kanz L, Schneidawind C, Schneidawind D. Jahnke S, et al. Among authors: secker ka. Front Immunol. 2019 Jul 9;10:1542. doi: 10.3389/fimmu.2019.01542. eCollection 2019. Front Immunol. 2019. PMID: 31354710 Free PMC article.