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Page 1
Patient-derived organoids model treatment response of metastatic gastrointestinal cancers.
Vlachogiannis G, Hedayat S, Vatsiou A, Jamin Y, Fernández-Mateos J, Khan K, Lampis A, Eason K, Huntingford I, Burke R, Rata M, Koh DM, Tunariu N, Collins D, Hulkki-Wilson S, Ragulan C, Spiteri I, Moorcraft SY, Chau I, Rao S, Watkins D, Fotiadis N, Bali M, Darvish-Damavandi M, Lote H, Eltahir Z, Smyth EC, Begum R, Clarke PA, Hahne JC, Dowsett M, de Bono J, Workman P, Sadanandam A, Fassan M, Sansom OJ, Eccles S, Starling N, Braconi C, Sottoriva A, Robinson SP, Cunningham D, Valeri N. Vlachogiannis G, et al. Among authors: eason k. Science. 2018 Feb 23;359(6378):920-926. doi: 10.1126/science.aao2774. Science. 2018. PMID: 29472484 Free PMC article.
Analytical Validation of Multiplex Biomarker Assay to Stratify Colorectal Cancer into Molecular Subtypes.
Ragulan C, Eason K, Fontana E, Nyamundanda G, Tarazona N, Patil Y, Poudel P, Lawlor RT, Del Rio M, Koo SL, Tan WS, Sclafani F, Begum R, Teixeira Mendes LS, Martineau P, Scarpa A, Cervantes A, Tan IB, Cunningham D, Sadanandam A. Ragulan C, et al. Among authors: eason k. Sci Rep. 2019 May 21;9(1):7665. doi: 10.1038/s41598-019-43492-0. Sci Rep. 2019. PMID: 31113981 Free PMC article.
Detection of postoperative plasma circulating tumour DNA and lack of CDX2 expression as markers of recurrence in patients with localised colon cancer.
Tarazona N, Gimeno-Valiente F, Gambardella V, Huerta M, Roselló S, Zuniga S, Calon A, Carbonell-Asins JA, Fontana E, Martinez-Ciarpaglini C, Eason K, Rentero-Garrido P, Fleitas T, Papaccio F, Moro-Valdezate D, Nyamundanda G, Castillo J, Espí A, Sadanandam A, Roda D, Cervantes A. Tarazona N, et al. Among authors: eason k. ESMO Open. 2020 Sep;5(5):e000847. doi: 10.1136/esmoopen-2020-000847. ESMO Open. 2020. PMID: 32967918 Free PMC article.
Intratumoral Transcriptome Heterogeneity Is Associated With Patient Prognosis and Sidedness in Patients With Colorectal Cancer Treated With Anti-EGFR Therapy From the CO.20 Trial.
Fontana E, Nyamundanda G, Cunningham D, Tu D, Cheang MCU, Jonker DJ, Siu LL, Sclafani F, Eason K, Ragulan C, Bali MA, Hulkki-Wilson S, Loree JM, Waring PM, Giordano M, Lawrence P, Rodrigues DN, Begum R, Shapiro JD, Price TJ, Cremolini C, Starling N, Pietrantonio F, Trusolino L, O'Callaghan CJ, Sadanandam A. Fontana E, et al. Among authors: eason k. JCO Precis Oncol. 2020 Sep 29;4:PO.20.00050. doi: 10.1200/PO.20.00050. eCollection 2020. JCO Precis Oncol. 2020. PMID: 33015526 Free PMC article.
Benefit from anti-EGFRs in RAS and BRAF wild-type metastatic transverse colon cancer: a clinical and molecular proof of concept study.
Cremolini C, Benelli M, Fontana E, Pagani F, Rossini D, Fucà G, Busico A, Conca E, Di Donato S, Loupakis F, Schirripa M, Lonardi S, Borelli B, Ongaro E, Eason K, Morano F, Casagrande M, Fassan M, Sadanandam A, de Braud F, Falcone A, Pietrantonio F. Cremolini C, et al. Among authors: eason k. ESMO Open. 2019 Mar 8;4(2):e000489. doi: 10.1136/esmoopen-2019-000489. eCollection 2019. ESMO Open. 2019. PMID: 30962964 Free PMC article.