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Mirogabalin Decreases Pain-like Behaviors by Inhibiting the Microglial/Macrophage Activation, p38MAPK Signaling, and Pronociceptive CCL2 and CCL5 Release in a Mouse Model of Neuropathic Pain.
Zajączkowska R, Pawlik K, Ciapała K, Piotrowska A, Ciechanowska A, Rojewska E, Kocot-Kępska M, Makuch W, Wordliczek J, Mika J. Zajączkowska R, et al. Among authors: ciapala k. Pharmaceuticals (Basel). 2023 Jul 19;16(7):1023. doi: 10.3390/ph16071023. Pharmaceuticals (Basel). 2023. PMID: 37513935 Free PMC article.
Promising anticonvulsant and/or analgesic compounds among 5-chloro-2- or 5-chloro-4-methyl derivatives of xanthone coupled to aminoalkanol moieties-Design, synthesis and pharmacological evaluation.
Mazur G, Pańczyk-Straszak K, Rapacz A, Kiszela J, Smolik M, Gawlik M, Walczak M, Czekajewska J, Poloczek C, Karczewska E, Żesławska E, Nitek W, Niedbał A, Leśniak J, Ciapala K, Pawlik K, Mika J, Waszkielewicz AM. Mazur G, et al. Among authors: ciapala k. Chem Biol Drug Des. 2023 Feb;101(2):278-325. doi: 10.1111/cbdd.14102. Epub 2022 Dec 16. Chem Biol Drug Des. 2023. PMID: 35713377
26 results