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Page 1
Recent advances on structural modifications of benzothiazoles and their conjugate systems as potential chemotherapeutics.
Expert Opin Investig Drugs. 2012 May;21(5):619-35. doi: 10.1517/13543784.2012.676043.
Expert Opin Investig Drugs. 2012.
PMID: 22493977
Review.
Antinociceptive Effects of a Novel α2/α3-Subtype Selective GABAA Receptor Positive Allosteric Modulator.
Lewter LA, Fisher JL, Siemian JN, Methuku KR, Poe MM, Cook JM, Li JX.
Lewter LA, et al.
ACS Chem Neurosci. 2017 Jun 21;8(6):1305-1312. doi: 10.1021/acschemneuro.6b00447. Epub 2017 Feb 13.
ACS Chem Neurosci. 2017.
PMID: 28150939
Free PMC article.
Item in Clipboard
Synthesis and Characterization of a Novel γ-Aminobutyric Acid Type A (GABAA) Receptor Ligand That Combines Outstanding Metabolic Stability, Pharmacokinetics, and Anxiolytic Efficacy.
Poe MM, Methuku KR, Li G, Verma AR, Teske KA, Stafford DC, Arnold LA, Cramer JW, Jones TM, Cerne R, Krambis MJ, Witkin JM, Jambrina E, Rehman S, Ernst M, Cook JM, Schkeryantz JM.
Poe MM, et al.
J Med Chem. 2016 Dec 8;59(23):10800-10806. doi: 10.1021/acs.jmedchem.6b01332. Epub 2016 Nov 28.
J Med Chem. 2016.
PMID: 27933953
Free PMC article.
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A Structure-Activity Relationship Comparison of Imidazodiazepines Binding at Kappa, Mu, and Delta Opioid Receptors and the GABAA Receptor.
Li G, Nieman AN, Mian MY, Zahn NM, Mikulsky BN, Poe MM, Methuku KR, Liu Y, Cook JM, Stafford DC, Arnold LA.
Li G, et al. Among authors: methuku kr.
Molecules. 2020 Aug 25;25(17):3864. doi: 10.3390/molecules25173864.
Molecules. 2020.
PMID: 32854311
Free PMC article.
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First In Vivo Testing of Compounds Targeting Group 3 Medulloblastomas Using an Implantable Microdevice as a New Paradigm for Drug Development.
Jonas O, Calligaris D, Methuku KR, Poe MM, Francois JP, Tranghese F, Changelian A, Sieghart W, Ernst M, Krummel DA, Cook JM, Pomeroy SL, Cima M, Agar NY, Langer R, Sengupta S.
Jonas O, et al.
J Biomed Nanotechnol. 2016 Jun;12(6):1297-302. doi: 10.1166/jbn.2016.2262.
J Biomed Nanotechnol. 2016.
PMID: 27319222
Free PMC article.
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Synthesis of aza and carbocyclic β-carbolines for the treatment of alcohol abuse. Regiospecific solution to the problem of 3,6-disubstituted β- and aza-β-carboline specificity.
Phani Babu Tiruveedhula VV, Methuku KR, Deschamps JR, Cook JM.
Phani Babu Tiruveedhula VV, et al.
Org Biomol Chem. 2015 Nov 21;13(43):10705-15. doi: 10.1039/c5ob01572c.
Org Biomol Chem. 2015.
PMID: 26349488
Free PMC article.
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