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Novel small molecule MRGPRX2 antagonists inhibit a murine model of allergic reaction.
J Allergy Clin Immunol. 2023 Apr;151(4):1110-1122. doi: 10.1016/j.jaci.2022.12.805. Epub 2022 Dec 26.
J Allergy Clin Immunol. 2023.
PMID: 36581009
Free article.
Unlocking the Non-IgE-Mediated Pseudo-Allergic Reaction Puzzle with Mas-Related G-Protein Coupled Receptor Member X2 (MRGPRX2).
Kumar M, Duraisamy K, Chow BK.
Kumar M, et al. Among authors: duraisamy k.
Cells. 2021 Apr 27;10(5):1033. doi: 10.3390/cells10051033.
Cells. 2021.
PMID: 33925682
Free PMC article.
Review.
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P17 induces chemotaxis and differentiation of monocytes via MRGPRX2-mediated mast cell-line activation.
Duraisamy K, Singh K, Kumar M, Lefranc B, Bonnafé E, Treilhou M, Leprince J, Chow BKC.
Duraisamy K, et al.
J Allergy Clin Immunol. 2022 Jan;149(1):275-291. doi: 10.1016/j.jaci.2021.04.040. Epub 2021 Jun 7.
J Allergy Clin Immunol. 2022.
PMID: 34111449
Free article.
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Role of SCTR/AT1aR heteromer in mediating ANGII-induced aldosterone secretion.
Bai J, Duraisamy K, Mak SOK, Allam A, Ajarem J, Li Z, Chow BKC.
Bai J, et al. Among authors: duraisamy k.
PLoS One. 2019 Sep 3;14(9):e0222005. doi: 10.1371/journal.pone.0222005. eCollection 2019.
PLoS One. 2019.
PMID: 31479491
Free PMC article.
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Protective Effect of Genistein against Compound 48/80 Induced Anaphylactoid Shock via Inhibiting MAS Related G Protein-Coupled Receptor X2 (MRGPRX2).
Kumar M, Singh K, Duraisamy K, A Allam A, Ajarem J, Kwok Chong Chow B.
Kumar M, et al. Among authors: duraisamy k.
Molecules. 2020 Feb 25;25(5):1028. doi: 10.3390/molecules25051028.
Molecules. 2020.
PMID: 32106575
Free PMC article.
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MRGPRB2/X2 and the analogous effects of its agonist and antagonist in DSS-induced colitis in mice.
Duraisamy K, Kumar M, Nawabjan A, Lo EKK, Hui Lin M, Lefranc B, Bonnafé E, Treilhou M, El-Nezami H, Leprince J, Chow BKC.
Duraisamy K, et al.
Biomed Pharmacother. 2024 Mar 27;174:116471. doi: 10.1016/j.biopha.2024.116471. Online ahead of print.
Biomed Pharmacother. 2024.
PMID: 38547764
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