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Page 1
Structural Insights Support Targeting ASK1 Kinase for Therapeutic Interventions.
Int J Mol Sci. 2021 Dec 13;22(24):13395. doi: 10.3390/ijms222413395.
Int J Mol Sci. 2021.
PMID: 34948191
Free PMC article.
Review.
Molecular basis and dual ligand regulation of tetrameric estrogen receptor α/14-3-3ζ protein complex.
Somsen BA, Sijbesma E, Leysen S, Honzejkova K, Visser EJ, Cossar PJ, Obšil T, Brunsveld L, Ottmann C.
Somsen BA, et al. Among authors: honzejkova k.
J Biol Chem. 2023 Jul;299(7):104855. doi: 10.1016/j.jbc.2023.104855. Epub 2023 May 22.
J Biol Chem. 2023.
PMID: 37224961
Free PMC article.
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14-3-3 protein inhibits CaMKK1 by blocking the kinase active site with its last two C-terminal helices.
Petrvalska O, Honzejkova K, Koupilova N, Herman P, Obsilova V, Obsil T.
Petrvalska O, et al. Among authors: honzejkova k.
Protein Sci. 2023 Nov;32(11):e4805. doi: 10.1002/pro.4805.
Protein Sci. 2023.
PMID: 37817008
Free PMC article.
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The cryo-EM structure of ASK1 reveals an asymmetric architecture allosterically modulated by TRX1.
Honzejkova K, Kosek D, Obsilova V, Obsil T.
Honzejkova K, et al.
Elife. 2024 Mar 27;13:RP95199. doi: 10.7554/eLife.95199.
Elife. 2024.
PMID: 38536085
Free PMC article.
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