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Signatures of recent activation identify a circulating T cell compartment containing tumor-specific antigen receptors with high avidity.
Purcarea A, Jarosch S, Barton J, Grassmann S, Pachmayr L, D'Ippolito E, Hammel M, Hochholzer A, Wagner KI, van den Berg JH, Buchholz VR, Haanen JBAG, Busch DH, Schober K. Purcarea A, et al. Among authors: wagner ki. Sci Immunol. 2022 Aug 12;7(74):eabm2077. doi: 10.1126/sciimmunol.abm2077. Epub 2022 Aug 12. Sci Immunol. 2022. PMID: 35960818
Recruitment of highly cytotoxic CD8+ T cell receptors in mild SARS-CoV-2 infection.
Wagner KI, Mateyka LM, Jarosch S, Grass V, Weber S, Schober K, Hammel M, Burrell T, Kalali B, Poppert H, Beyer H, Schambeck S, Holdenrieder S, Strötges-Achatz A, Haselmann V, Neumaier M, Erber J, Priller A, Yazici S, Roggendorf H, Odendahl M, Tonn T, Dick A, Witter K, Mijočević H, Protzer U, Knolle PA, Pichlmair A, Crowell CS, Gerhard M, D'Ippolito E, Busch DH. Wagner KI, et al. Cell Rep. 2022 Jan 11;38(2):110214. doi: 10.1016/j.celrep.2021.110214. Epub 2021 Dec 17. Cell Rep. 2022. PMID: 34968416 Free PMC article.
CMV seropositivity is a potential novel risk factor for severe COVID-19 in non-geriatric patients.
Weber S, Kehl V, Erber J, Wagner KI, Jetzlsperger AM, Burrell T, Schober K, Schommers P, Augustin M, Crowell CS, Gerhard M, Winter C, Moosmann A, Spinner CD, Protzer U, Hoffmann D, D'Ippolito E, Busch DH. Weber S, et al. Among authors: wagner ki. PLoS One. 2022 May 25;17(5):e0268530. doi: 10.1371/journal.pone.0268530. eCollection 2022. PLoS One. 2022. PMID: 35613127 Free PMC article.
Single-cell RNA sequencing reveals ex vivo signatures of SARS-CoV-2-reactive T cells through 'reverse phenotyping'.
Fischer DS, Ansari M, Wagner KI, Jarosch S, Huang Y, Mayr CH, Strunz M, Lang NJ, D'Ippolito E, Hammel M, Mateyka L, Weber S, Wolff LS, Witter K, Fernandez IE, Leuschner G, Milger K, Frankenberger M, Nowak L, Heinig-Menhard K, Koch I, Stoleriu MG, Hilgendorff A, Behr J, Pichlmair A, Schubert B, Theis FJ, Busch DH, Schiller HB, Schober K. Fischer DS, et al. Among authors: wagner ki. Nat Commun. 2021 Jul 26;12(1):4515. doi: 10.1038/s41467-021-24730-4. Nat Commun. 2021. PMID: 34312385 Free PMC article.