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Cryptic aberrations may allow more accurate prognostic classification of patients with myelodysplastic syndromes and clonal evolution.
Svobodova K, Lhotska H, Hodanova L, Pavlistova L, Vesela D, Belickova M, Vesela J, Brezinova J, Sarova I, Izakova S, Lizcova L, Siskova M, Jonasova A, Cermak J, Michalova K, Zemanova Z. Svobodova K, et al. Genes Chromosomes Cancer. 2020 Jul;59(7):396-405. doi: 10.1002/gcc.22841. Epub 2020 Mar 25. Genes Chromosomes Cancer. 2020. PMID: 32170980
High frequency of dicentric chromosomes detected by multi-centromeric FISH in patients with acute myeloid leukemia and complex karyotype.
Sarova I, Brezinova J, Zemanova Z, Ransdorfova S, Svobodova K, Izakova S, Pavlistova L, Lizcova L, Berkova A, Skipalova K, Hodanova L, Salek C, Jonasova A, Michalova K. Sarova I, et al. Among authors: svobodova k. Leuk Res. 2018 May;68:85-89. doi: 10.1016/j.leukres.2018.03.009. Epub 2018 Mar 19. Leuk Res. 2018. PMID: 29574397
Cotargeting of BCL2 with Venetoclax and MCL1 with S63845 Is Synthetically Lethal In Vivo in Relapsed Mantle Cell Lymphoma.
Prukova D, Andera L, Nahacka Z, Karolova J, Svaton M, Klanova M, Havranek O, Soukup J, Svobodova K, Zemanova Z, Tuskova D, Pokorna E, Helman K, Forsterova K, Pacheco-Blanco M, Vockova P, Berkova A, Fronkova E, Trneny M, Klener P. Prukova D, et al. Among authors: svobodova k. Clin Cancer Res. 2019 Jul 15;25(14):4455-4465. doi: 10.1158/1078-0432.CCR-18-3275. Epub 2019 Apr 19. Clin Cancer Res. 2019. PMID: 31004002
Molecular cytogenetic analysis of dicentric chromosomes in acute myeloid leukemia.
Sarova I, Brezinova J, Zemanova Z, Ransdorfova S, Izakova S, Svobodova K, Pavlistova L, Berkova A, Cermak J, Jonasova A, Siskova M, Michalova K. Sarova I, et al. Among authors: svobodova k. Leuk Res. 2016 Apr;43:51-7. doi: 10.1016/j.leukres.2016.01.001. Epub 2016 Jan 8. Leuk Res. 2016. PMID: 26821593 Clinical Trial.
Copy number neutral loss of heterozygosity at 17p and homozygous mutations of TP53 are associated with complex chromosomal aberrations in patients newly diagnosed with myelodysplastic syndromes.
Svobodova K, Zemanova Z, Lhotska H, Novakova M, Podskalska L, Belickova M, Brezinova J, Sarova I, Izakova S, Lizcova L, Berkova A, Siskova M, Jonasova A, Cermak J, Michalova K. Svobodova K, et al. Leuk Res. 2016 Mar;42:7-12. doi: 10.1016/j.leukres.2016.01.009. Epub 2016 Jan 24. Leuk Res. 2016. PMID: 26851439