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Seladelpar efficacy and safety at 3 months in patients with primary biliary cholangitis: ENHANCE, a phase 3, randomized, placebo-controlled study.
Hirschfield GM, Shiffman ML, Gulamhusein A, Kowdley KV, Vierling JM, Levy C, Kremer AE, Zigmond E, Andreone P, Gordon SC, Bowlus CL, Lawitz EJ, Aspinall RJ, Pratt DS, Raikhelson K, Gonzalez-Huezo MS, Heneghan MA, Jeong SH, Ladrón de Guevara AL, Mayo MJ, Dalekos GN, Drenth JPH, Janczewska E, Leggett BA, Nevens F, Vargas V, Zuckerman E, Corpechot C, Fassio E, Hinrichsen H, Invernizzi P, Trivedi PJ, Forman L, Jones DEJ, Ryder SD, Swain MG, Steinberg A, Boudes PF, Choi YJ, McWherter CA; ENHANCE Study Group*. Hirschfield GM, et al. Hepatology. 2023 Aug 1;78(2):397-415. doi: 10.1097/HEP.0000000000000395. Epub 2023 Apr 6. Hepatology. 2023. PMID: 37386786 Free PMC article. Clinical Trial.
Recent Advances in BLV Research.
Barez PY, de Brogniez A, Carpentier A, Gazon H, Gillet N, Gutiérrez G, Hamaidia M, Jacques JR, Perike S, Neelature Sriramareddy S, Renotte N, Staumont B, Reichert M, Trono K, Willems L. Barez PY, et al. Viruses. 2015 Nov 24;7(11):6080-8. doi: 10.3390/v7112929. Viruses. 2015. PMID: 26610551 Free PMC article. Review.
Negative elongation factor is essential for endometrial function.
Hewitt SC, Li R, Adams N, Winuthayanon W, Hamilton KJ, Donoghue LJ, Lierz SL, Garcia M, Lydon JP, DeMayo FJ, Adelman K, Korach KS. Hewitt SC, et al. FASEB J. 2019 Feb;33(2):3010-3023. doi: 10.1096/fj.201801752. Epub 2018 Oct 17. FASEB J. 2019. PMID: 30332301 Free PMC article.
Promoter proximal enrichment of Pol II occurs at uterine genes relevant to reproductive biology; thus, we hypothesized that pausing might impact endometrial response by coordinating hormonal signals involved in establishing and maintaining pregnancy. We deleted the NELF-B
Promoter proximal enrichment of Pol II occurs at uterine genes relevant to reproductive biology; thus, we hypothesized that pausing might im …
Optimising treatment resources for OCD: a review of the evidence base for technology-enhanced delivery.
Lovell K, Bee P. Lovell K, et al. J Ment Health. 2011 Dec;20(6):525-42. doi: 10.3109/09638237.2011.608745. J Ment Health. 2011. PMID: 22126631 Review.
The questions posed by the review were (a) are technology-assisted treatments clinically effective, (b) are patient outcomes durable and (c) are more innovative services deemed acceptable by those individuals who engage in them? ...
The questions posed by the review were (a) are technology-assisted treatments clinically effective, (b) are patient outcomes durable …
Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration.
Wilman HR, Parisinos CA, Atabaki-Pasdar N, Kelly M, Thomas EL, Neubauer S; IMI DIRECT Consortium; Mahajan A, Hingorani AD, Patel RS, Hemingway H, Franks PW, Bell JD, Banerjee R, Yaghootkar H. Wilman HR, et al. J Hepatol. 2019 Sep;71(3):594-602. doi: 10.1016/j.jhep.2019.05.032. Epub 2019 Jun 19. J Hepatol. 2019. PMID: 31226389 Free PMC article.
Analysis of marine diversity and anthropogenic pressures on Seixas coral reef ecosystem (northeastern Brazil).
Massei K, Souza MCS, Silva RMD, Costa DA, Vianna PCG, Crispim MC, Miranda GEC, Eggertsen L, Eloy CC, Santos CAG. Massei K, et al. Sci Total Environ. 2023 Dec 20;905:166984. doi: 10.1016/j.scitotenv.2023.166984. Epub 2023 Sep 11. Sci Total Environ. 2023. PMID: 37704134
Utilizing 25 monitoring transects, subdivided into 1 m(2) quadrants, the marine diversity was meticulously evaluated through innovative procedures including (a) sedimentological and geochemical field surveys, (b) application of Shannon-Weaver diversity and Simpson dominanc …
Utilizing 25 monitoring transects, subdivided into 1 m(2) quadrants, the marine diversity was meticulously evaluated through innovative proc …
Classification of the midpalatal suture maturation in individuals older than 15 years: a cone beam computed tomographic study.
Reis LG, Ribeiro RA, Vitral RWF, Reis HN, Devito KL. Reis LG, et al. Surg Radiol Anat. 2020 Sep;42(9):1043-1049. doi: 10.1007/s00276-020-02518-3. Epub 2020 Jun 16. Surg Radiol Anat. 2020. PMID: 32556669
METHODS: Tomographic images in axial sections of the MPS of 289 female individuals and 198 male individuals aged between 15 and 40 years were analyzed and classified in stages of maturation (A, B, C, D, and E), stage A represents the earliest maturation stage of the …
METHODS: Tomographic images in axial sections of the MPS of 289 female individuals and 198 male individuals aged between 15 and 40 years wer …
Exercise protects synaptic density in a rat model of Parkinson's disease.
Binda KH, Lillethorup TP, Real CC, Bærentzen SL, Nielsen MN, Orlowski D, Brooks DJ, Chacur M, Landau AM. Binda KH, et al. Exp Neurol. 2021 Aug;342:113741. doi: 10.1016/j.expneurol.2021.113741. Epub 2021 May 11. Exp Neurol. 2021. PMID: 33965411 Free article.
OBJECTIVES: In a parkinsonian rat model, we test the hypotheses that exercise: (a) increases synaptic density and reduces neuroinflammation and (b) lowers the nociceptive threshold by increasing mu-opioid receptor expression. ...
OBJECTIVES: In a parkinsonian rat model, we test the hypotheses that exercise: (a) increases synaptic density and reduces neuroinflammation …
31 results