Preparation of a library of EDTA amide x-aminenaphthalene-y-sulfonic acid derivatives on solid phase and their fluorescence behavior toward transition metals

J Comb Chem. 2009 Nov-Dec;11(6):1030-7. doi: 10.1021/cc900075r.

Abstract

In this work, we report the synthesis of a combinatorial library of 80 derivatives of EDTA amide x-aminenaphthalene-y-sulfonic acid on four different supports with variable length linker. The sensing fluorescence behavior of these materials for transitions metals was studied by packing the beads into a conventional flow-through cell in a continuous flow injection set up. The fluorescence emission response of these materials shows that sensors supported in Argopore (a) with the fluorescence moiety of 1-aminenaphthalene-4-sulfonic acid behaves like dosimeter for copper.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Combinatorial Chemistry Techniques / methods*
  • Fluorescence*
  • Molecular Structure
  • Naphthalenes / chemical synthesis*
  • Naphthalenes / chemistry*
  • Small Molecule Libraries
  • Stereoisomerism
  • Sulfonic Acids / chemical synthesis*
  • Sulfonic Acids / chemistry*
  • Time Factors
  • Transition Elements / chemistry*

Substances

  • Naphthalenes
  • Small Molecule Libraries
  • Sulfonic Acids
  • Transition Elements