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Page 1
Effects of insulin and pathway inhibitors on the PI3K-Akt-mTOR phosphorylation profile in acute myeloid leukemia cells.
Nepstad I, Hatfield KJ, Grønningsæter IS, Aasebø E, Hernandez-Valladares M, Hagen KM, Rye KP, Berven FS, Selheim F, Reikvam H, Bruserud Ø. Nepstad I, et al. Among authors: hagen km. Signal Transduct Target Ther. 2019 Jun 19;4:20. doi: 10.1038/s41392-019-0050-0. eCollection 2019. Signal Transduct Target Ther. 2019. PMID: 31240133 Free PMC article.
CXXC5 (retinoid-inducible nuclear factor, RINF) is a potential therapeutic target in high-risk human acute myeloid leukemia.
Astori A, Fredly H, Aloysius TA, Bullinger L, Mansat-De Mas V, de la Grange P, Delhommeau F, Hagen KM, Récher C, Dusanter-Fourt I, Knappskog S, Lillehaug JR, Pendino F, Bruserud Ø. Astori A, et al. Among authors: hagen km. Oncotarget. 2013 Sep;4(9):1438-48. doi: 10.18632/oncotarget.1195. Oncotarget. 2013. PMID: 23988457 Free PMC article.
Expansion of myeloid derived suppressor cells correlates with number of T regulatory cells and disease progression in myelodysplastic syndrome.
Kittang AO, Kordasti S, Sand KE, Costantini B, Kramer AM, Perezabellan P, Seidl T, Rye KP, Hagen KM, Kulasekararaj A, Bruserud Ø, Mufti GJ. Kittang AO, et al. Among authors: hagen km. Oncoimmunology. 2015 Jun 24;5(2):e1062208. doi: 10.1080/2162402X.2015.1062208. eCollection 2016 Feb. Oncoimmunology. 2015. PMID: 27057428 Free PMC article.
Expression of the potential therapeutic target CXXC5 in primary acute myeloid leukemia cells - high expression is associated with adverse prognosis as well as altered intracellular signaling and transcriptional regulation.
Bruserud Ø, Reikvam H, Fredly H, Skavland J, Hagen KM, van Hoang TT, Brenner AK, Kadi A, Astori A, Gjertsen BT, Pendino F. Bruserud Ø, et al. Among authors: hagen km. Oncotarget. 2015 Feb 20;6(5):2794-811. doi: 10.18632/oncotarget.3056. Oncotarget. 2015. PMID: 25605239 Free PMC article.
The cytokine-mediated crosstalk between primary human acute myeloid cells and mesenchymal stem cells alters the local cytokine network and the global gene expression profile of the mesenchymal cells.
Reikvam H, Brenner AK, Hagen KM, Liseth K, Skrede S, Hatfield KJ, Bruserud Ø. Reikvam H, et al. Among authors: hagen km. Stem Cell Res. 2015 Nov;15(3):530-541. doi: 10.1016/j.scr.2015.09.008. Epub 2015 Sep 25. Stem Cell Res. 2015. PMID: 26468600 Free article.