Karen E. Christensen - Search Results

Year	Number of Results
2002	1
2003	1
2004	1
2005	2
2006	1
2008	1
2009	1
2010	1
2012	1
2013	2
2014	1
2015	2
2016	2
2017	1
2018	3
2019	1
2020	3
2021	2
2022	1
2024	2

1

Mitochondrial methylenetetrahydrofolate dehydrogenase, methenyltetrahydrofolate cyclohydrolase, and formyltetrahydrofolate synthetases.

Christensen KE, Mackenzie RE. Christensen KE, et al. Vitam Horm. 2008;79:393-410. doi: 10.1016/S0083-6729(08)00414-7. Vitam Horm. 2008. PMID: 18804703 Review.

2

Mitochondrial one-carbon metabolism is adapted to the specific needs of yeast, plants and mammals.

Christensen KE, MacKenzie RE. Christensen KE, et al. Bioessays. 2006 Jun;28(6):595-605. doi: 10.1002/bies.20420. Bioessays. 2006. PMID: 16700064 Review.

3

The 677C > T variant in methylenetetrahydrofolate reductase causes morphological and functional cerebrovascular deficits in mice.

Reagan AM, Christensen KE, Graham LC, Bedwell AA, Eldridge K, Speedy R, Figueiredo LL, Persohn SC, Bottiglieri T, Nho K, Sasner M, Territo PR, Rozen R, Howell GR. Reagan AM, et al. Among authors: christensen ke. J Cereb Blood Flow Metab. 2022 Dec;42(12):2333-2350. doi: 10.1177/0271678X221122644. Epub 2022 Sep 1. J Cereb Blood Flow Metab. 2022. PMID: 36050860 Free PMC article.

4

Mild Methylenetetrahydrofolate Reductase Deficiency Alters Inflammatory and Lipid Pathways in Liver.

Leclerc D, Christensen KE, Cauvi O, Yang E, Fournelle F, Bahous RH, Malysheva OV, Deng L, Wu Q, Zhou Z, Gao ZH, Chaurand P, Caudill MA, Rozen R. Leclerc D, et al. Among authors: christensen ke. Mol Nutr Food Res. 2019 Feb;63(3):e1801001. doi: 10.1002/mnfr.201801001. Epub 2018 Nov 23. Mol Nutr Food Res. 2019. PMID: 30408316

5

High folic acid intake increases methylation-dependent expression of Lsr and dysregulates hepatic cholesterol homeostasis.

Leclerc D, Jelinek J, Christensen KE, Issa JJ, Rozen R. Leclerc D, et al. Among authors: christensen ke. J Nutr Biochem. 2021 Feb;88:108554. doi: 10.1016/j.jnutbio.2020.108554. Epub 2020 Nov 19. J Nutr Biochem. 2021. PMID: 33220403

6

Biochemical analysis of patients with mutations in MTHFD1 and a diagnosis of methylenetetrahydrofolate dehydrogenase 1 deficiency.

Bidla G, Watkins D, Chéry C, Froese DS, Ells C, Kerachian M, Saskin A, Christensen KE, Gilfix BM, Guéant JL, Rosenblatt DS. Bidla G, et al. Among authors: christensen ke. Mol Genet Metab. 2020 Jul;130(3):179-182. doi: 10.1016/j.ymgme.2020.04.008. Epub 2020 May 5. Mol Genet Metab. 2020. PMID: 32414565

7

Mild Choline Deficiency and MTHFD1 Synthetase Deficiency Interact to Increase Incidence of Developmental Delays and Defects in Mice.

Christensen KE, Malysheva OV, Carlin S, Matias F, MacFarlane AJ, Jacobs RL, Caudill MA, Rozen R. Christensen KE, et al. Nutrients. 2021 Dec 28;14(1):127. doi: 10.3390/nu14010127. Nutrients. 2021. PMID: 35011003 Free PMC article.

8

The molecular basis of glutamate formiminotransferase deficiency.

Hilton JF, Christensen KE, Watkins D, Raby BA, Renaud Y, de la Luna S, Estivill X, MacKenzie RE, Hudson TJ, Rosenblatt DS. Hilton JF, et al. Among authors: christensen ke. Hum Mutat. 2003 Jul;22(1):67-73. doi: 10.1002/humu.10236. Hum Mutat. 2003. PMID: 12815595

9

Testicular MTHFR deficiency may explain sperm DNA hypomethylation associated with high dose folic acid supplementation.

Aarabi M, Christensen KE, Chan D, Leclerc D, Landry M, Ly L, Rozen R, Trasler J. Aarabi M, et al. Among authors: christensen ke. Hum Mol Genet. 2018 Apr 1;27(7):1123-1135. doi: 10.1093/hmg/ddy021. Hum Mol Genet. 2018. PMID: 29360980 Free PMC article.

10

Folate Deficiency and/or the Genetic Variant Mthfr^{677C >T} Can Drive Hepatic Fibrosis or Steatosis in Mice, in a Sex-Specific Manner.

Leclerc D, Christensen KE, Reagan AM, Keser V, Luan Y, Malysheva OV, Wasek B, Bottiglieri T, Caudill MA, Howell GR, Rozen R. Leclerc D, et al. Among authors: christensen ke. Mol Nutr Food Res. 2024 Mar;68(5):e2300355. doi: 10.1002/mnfr.202300355. Epub 2024 Feb 7. Mol Nutr Food Res. 2024. PMID: 38327171

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