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Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.
RECOVERY Collaborative Group. RECOVERY Collaborative Group. Lancet. 2021 May 1;397(10285):1637-1645. doi: 10.1016/S0140-6736(21)00676-0. Lancet. 2021. PMID: 33933206 Free PMC article. Clinical Trial.
Those trial participants with hypoxia (oxygen saturation <92% on air or requiring oxygen therapy) and evidence of systemic inflammation (C-reactive protein 75 mg/L) were eligible for random assignment in a 1:1 ratio to usual standard of care alone versus usual standard of care …
Those trial participants with hypoxia (oxygen saturation <92% on air or requiring oxygen therapy) and evidence of systemic inflammation ( …
Global variation in postoperative mortality and complications after cancer surgery: a multicentre, prospective cohort study in 82 countries.
GlobalSurg Collaborative and National Institute for Health Research Global Health Research Unit on Global Surgery. GlobalSurg Collaborative and National Institute for Health Research Global Health Research Unit on Global Surgery. Lancet. 2021 Jan 30;397(10272):387-397. doi: 10.1016/S0140-6736(21)00001-5. Epub 2021 Jan 21. Lancet. 2021. PMID: 33485461 Free PMC article.
Triglyceride Lowering with Pemafibrate to Reduce Cardiovascular Risk.
Das Pradhan A, Glynn RJ, Fruchart JC, MacFadyen JG, Zaharris ES, Everett BM, Campbell SE, Oshima R, Amarenco P, Blom DJ, Brinton EA, Eckel RH, Elam MB, Felicio JS, Ginsberg HN, Goudev A, Ishibashi S, Joseph J, Kodama T, Koenig W, Leiter LA, Lorenzatti AJ, Mankovsky B, Marx N, Nordestgaard BG, Páll D, Ray KK, Santos RD, Soran H, Susekov A, Tendera M, Yokote K, Paynter NP, Buring JE, Libby P, Ridker PM; PROMINENT Investigators. Das Pradhan A, et al. N Engl J Med. 2022 Nov 24;387(21):1923-1934. doi: 10.1056/NEJMoa2210645. Epub 2022 Nov 5. N Engl J Med. 2022. PMID: 36342113 Clinical Trial.
A dense 0.1-solar-mass star in a 51-minute-orbital-period eclipsing binary.
Burdge KB, El-Badry K, Marsh TR, Rappaport S, Brown WR, Caiazzo I, Chakrabarty D, Dhillon VS, Fuller J, Gänsicke BT, Graham MJ, Kara E, Kulkarni SR, Littlefair SP, Mróz P, Rodríguez-Gil P, Roestel JV, Simcoe RA, Bellm EC, Drake AJ, Dekany RG, Groom SL, Laher RR, Masci FJ, Riddle R, Smith RM, Prince TA. Burdge KB, et al. Nature. 2022 Oct;610(7932):467-471. doi: 10.1038/s41586-022-05195-x. Epub 2022 Oct 5. Nature. 2022. PMID: 36198793 Free article.
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