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PBRM1 mutations might render a subtype of biliary tract cancers sensitive to drugs targeting the DNA damage repair system.
Zimmer K, Kocher F, Untergasser G, Kircher B, Amann A, Baca Y, Xiu J, Korn WM, Berger MD, Lenz HJ, Puccini A, Fontana E, Shields AF, Marshall JL, Hall M, El-Deiry WS, Hsiehchen D, Macarulla T, Tabernero J, Pichler R, Khushman M, Manne U, Lou E, Wolf D, Sokolova V, Schnaiter S, Zeimet AG, Gulhati P, Widmann G, Seeber A. Zimmer K, et al. NPJ Precis Oncol. 2023 Jul 3;7(1):64. doi: 10.1038/s41698-023-00409-5. NPJ Precis Oncol. 2023. PMID: 37400502 Free PMC article.
Comprehensive Analysis of R-Spondin Fusions and RNF43 Mutations Implicate Novel Therapeutic Options in Colorectal Cancer.
Seeber A, Battaglin F, Zimmer K, Kocher F, Baca Y, Xiu J, Spizzo G, Novotny-Diermayr V, Rieder D, Puccini A, Swensen J, Ellis M, Goldberg RM, Grothey A, Shields AF, Marshall JL, Weinberg BA, Sackstein PE, Lim KH, Tan GS, Nabhan C, Korn WM, Amann A, Trajanoski Z, Berger MD, Lou E, Wolf D, Lenz HJ. Seeber A, et al. Among authors: zimmer k. Clin Cancer Res. 2022 May 2;28(9):1863-1870. doi: 10.1158/1078-0432.CCR-21-3018. Clin Cancer Res. 2022. PMID: 35254413 Free PMC article.
Multi-omic Characterization of Pancreatic Ductal Adenocarcinoma Relates CXCR4 mRNA Expression Levels to Potential Clinical Targets.
Kocher F, Puccini A, Untergasser G, Martowicz A, Zimmer K, Pircher A, Baca Y, Xiu J, Haybaeck J, Tymoszuk P, Goldberg RM, Petrillo A, Shields AF, Salem ME, Marshall JL, Hall M, Korn WM, Nabhan C, Battaglin F, Lenz HJ, Lou E, Choo SP, Toh CK, Gasteiger S, Pichler R, Wolf D, Seeber A. Kocher F, et al. Among authors: zimmer k. Clin Cancer Res. 2022 Nov 14;28(22):4957-4967. doi: 10.1158/1078-0432.CCR-22-0275. Clin Cancer Res. 2022. PMID: 36112544 Free PMC article.
WRN-Mutated Colorectal Cancer Is Characterized by a Distinct Genetic Phenotype.
Zimmer K, Puccini A, Xiu J, Baca Y, Spizzo G, Lenz HJ, Battaglin F, Goldberg RM, Grothey A, Shields AF, Salem ME, Marshall JL, Korn WM, Wolf D, Kocher F, Seeber A. Zimmer K, et al. Cancers (Basel). 2020 May 22;12(5):1319. doi: 10.3390/cancers12051319. Cancers (Basel). 2020. PMID: 32455893 Free PMC article.
Molecular characteristics of BRCA1/2 and PALB2 mutations in pancreatic ductal adenocarcinoma.
Seeber A, Zimmer K, Kocher F, Puccini A, Xiu J, Nabhan C, Elliott A, Goldberg RM, Grothey A, Shields AF, Battaglin F, El-Deiry WS, Philip PA, Marshall JL, Hall M, Korn WM, Lenz HJ, Wolf D, Feistritzer C, Spizzo G. Seeber A, et al. Among authors: zimmer k. ESMO Open. 2020 Nov;5(6):e000942. doi: 10.1136/esmoopen-2020-000942. ESMO Open. 2020. PMID: 33229504 Free PMC article.