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Does lower extremity fracture fixation technique influence neurologic outcomes in patients with traumatic brain injury? The EAST Brain vs. Bone multicenter trial.
Ghneim M, Kufera J, Zhang A, Penaloza-Villalobos L, Swentek L, Watras J, Smith A, Hahn A, Rodriguez Mederos D, Dickhudt TJ, Laverick P, Cunningham K, Norwood S, Fernandez L, Jacobson LE, Williams JM, Lottenberg L, Azar F, Shillinglaw W, Slivinski A, Nahmias J, Donnelly M, Bala M, Egodage T, Zhu C, Udekwu PO, Norton H, Dunn JA, Baer R, McBride K, Santos AP, Shrestha K, Metzner CJ, Murphy JM, Schroeppel TJ, Stillman Z, O'Connor R, Johnson D, Berry C, Ratner M, Reynolds JK, Humphrey M, Scott M, Hickman ZL, Twelker K, Legister C, Glass NE, Siebenburgen C, Palmer B, Semon GR, Lieser M, McDonald H, Bugaev N, LeClair MJ, Stein D; Brain vs. Bone Study Group. Ghneim M, et al. Among authors: cunningham k. J Trauma Acute Care Surg. 2023 Oct 1;95(4):516-523. doi: 10.1097/TA.0000000000004095. Epub 2023 Jun 19. J Trauma Acute Care Surg. 2023. PMID: 37335182
Mortality after emergent trauma laparotomy: A multicenter, retrospective study.
Harvin JA, Maxim T, Inaba K, Martinez-Aguilar MA, King DR, Choudhry AJ, Zielinski MD, Akinyeye S, Todd SR, Griffin RL, Kerby JD, Bailey JA, Livingston DH, Cunningham K, Stein DM, Cattin L, Bulger EM, Wilson A, Undurraga Perl VJ, Schreiber MA, Cherry-Bukowiec JR, Alam HB, Holcomb JB. Harvin JA, et al. Among authors: cunningham k. J Trauma Acute Care Surg. 2017 Sep;83(3):464-468. doi: 10.1097/TA.0000000000001619. J Trauma Acute Care Surg. 2017. PMID: 28598906 Free PMC article.
The physiology of failure: Identifying risk factors for mortality in emergency general surgery patients using a regional health system integrated electronic medical record.
Baimas-George M, Ross SW, Hetherington T, Kowalkowski M, Wang H, Thompson K, Cunningham K, Matthews BD, May AK, Reinke CE. Baimas-George M, et al. Among authors: cunningham k. J Trauma Acute Care Surg. 2022 Sep 1;93(3):409-417. doi: 10.1097/TA.0000000000003618. Epub 2022 Apr 12. J Trauma Acute Care Surg. 2022. PMID: 35998289
Activation of an essential calcium signaling pathway in Saccharomyces cerevisiae by Kch1 and Kch2, putative low-affinity potassium transporters.
Stefan CP, Zhang N, Sokabe T, Rivetta A, Slayman CL, Montell C, Cunningham KW. Stefan CP, et al. Among authors: cunningham kw. Eukaryot Cell. 2013 Feb;12(2):204-14. doi: 10.1128/EC.00299-12. Epub 2012 Nov 30. Eukaryot Cell. 2013. PMID: 23204190 Free PMC article.
When forcibly overexpressed, Kch1 and Kch2 localized to the plasma membrane and activated HACS in a fashion that depended on extracellular K(+) but not pheromones. They also promoted growth of trk1 trk2 mutant cells in low K(+) environments, suggesting they promote …
When forcibly overexpressed, Kch1 and Kch2 localized to the plasma membrane and activated HACS in a fashion that depended on extracellular …
Infection after penetrating brain injury-An Eastern Association for the Surgery of Trauma multicenter study oral presentation at the 32nd annual meeting of the Eastern Association for the Surgery of Trauma, January 15-19, 2019, in Austin, Texas.
Harmon LA, Haase DJ, Kufera JA, Adnan S, Cabral D, Lottenberg L, Cunningham KW, Bonne S, Burgess J, Etheridge J, Rehbein JL, Semon G, Noorbakhsh MR, Cragun BN, Agrawal V, Truitt M, Marcotte J, Goldenberg A, Behbahaninia M, Keric N, Hammer PM, Nahmias J, Grigorian A, Turay D, Chakravarthy V, Lalchandani P, Kim D, Chapin T, Dunn J, Portillo V, Schroeppel T, Stein DM. Harmon LA, et al. Among authors: cunningham kw. J Trauma Acute Care Surg. 2019 Jul;87(1):61-67. doi: 10.1097/TA.0000000000002327. J Trauma Acute Care Surg. 2019. PMID: 31033883
Domain architecture of the regulators of calcineurin (RCANs) and identification of a divergent RCAN in yeast.
Mehta S, Li H, Hogan PG, Cunningham KW. Mehta S, et al. Among authors: cunningham kw. Mol Cell Biol. 2009 May;29(10):2777-93. doi: 10.1128/MCB.01197-08. Epub 2009 Mar 9. Mol Cell Biol. 2009. PMID: 19273587 Free PMC article.
The dual effects of RCANs on calcineurin were examined by performing structure-function analyses on yeast Rcn1 and human RCAN1 (a.k.a. DSCR1, MCIP1, and calcipressin 1) proteins expressed at a variety of different levels in yeast. ...
The dual effects of RCANs on calcineurin were examined by performing structure-function analyses on yeast Rcn1 and human RCAN1 (a.k.a …
Kch1 family proteins mediate essential responses to endoplasmic reticulum stresses in the yeasts Saccharomyces cerevisiae and Candida albicans.
Stefan CP, Cunningham KW. Stefan CP, et al. Among authors: cunningham kw. J Biol Chem. 2013 Nov 29;288(48):34861-70. doi: 10.1074/jbc.M113.508705. Epub 2013 Oct 18. J Biol Chem. 2013. PMID: 24142703 Free PMC article.
The mechanisms linking ER stress to HACS activation are not known. Here we show that Kch1, a recently identified low affinity K(+) transporter in the plasma membrane of Saccharomyces cerevisiae, is up-regulated in response to several ER stressors and necessary for HACS act …
The mechanisms linking ER stress to HACS activation are not known. Here we show that Kch1, a recently identified low affinity K(+) tr …