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The epigenetic state of IL-4-polarized macrophages enables inflammatory cistromic expansion and extended synergistic response to TLR ligands.
Czimmerer Z, Halasz L, Daniel B, Varga Z, Bene K, Domokos A, Hoeksema M, Shen Z, Berger WK, Cseh T, Jambrovics K, Kolostyak Z, Fenyvesi F, Varadi J, Poliska S, Hajas G, Szatmari I, Glass CK, Bacsi A, Nagy L. Czimmerer Z, et al. Among authors: jambrovics k. Immunity. 2022 Nov 8;55(11):2006-2026.e6. doi: 10.1016/j.immuni.2022.10.004. Epub 2022 Nov 1. Immunity. 2022. PMID: 36323312 Free PMC article.
The transcriptional control of the VEGFA-VEGFR1 (FLT1) axis in alternatively polarized murine and human macrophages.
Domokos A, Varga Z, Jambrovics K, Caballero-Sánchez N, Szabo E, Nagy G, Scholtz B, Halasz L, Varadi E, Bene KP, Mazlo A, Bacsi A, Jeney V, Szebeni GJ, Nagy L, Czimmerer Z. Domokos A, et al. Among authors: jambrovics k. Front Immunol. 2023 May 4;14:1168635. doi: 10.3389/fimmu.2023.1168635. eCollection 2023. Front Immunol. 2023. PMID: 37215144 Free PMC article.
IL-15 Trans-Presentation Is an Autonomous, Antigen-Independent Process.
Kenesei Á, Volkó J, Szalóki N, Mocsár G, Jambrovics K, Balajthy Z, Bodnár A, Tóth K, Waldmann TA, Vámosi G. Kenesei Á, et al. Among authors: jambrovics k. J Immunol. 2021 Nov 15;207(10):2489-2500. doi: 10.4049/jimmunol.2100277. Epub 2021 Oct 15. J Immunol. 2021. PMID: 34654688 Free PMC article.
IL-2 receptors preassemble and signal in the ER/Golgi causing resistance to antiproliferative anti-IL-2Rα therapies.
Volkó J, Kenesei Á, Zhang M, Várnai P, Mocsár G, Petrus MN, Jambrovics K, Balajthy Z, Müller G, Bodnár A, Tóth K, Waldmann TA, Vámosi G. Volkó J, et al. Among authors: jambrovics k. Proc Natl Acad Sci U S A. 2019 Oct 15;116(42):21120-21130. doi: 10.1073/pnas.1901382116. Epub 2019 Sep 30. Proc Natl Acad Sci U S A. 2019. PMID: 31570576 Free PMC article.
Microcystin-LR, a protein phosphatase inhibitor, induces alterations in mitotic chromatin and microtubule organization leading to the formation of micronuclei in Vicia faba.
Beyer D, Tándor I, Kónya Z, Bátori R, Roszik J, Vereb G, Erdodi F, Vasas G, M-Hamvas M, Jambrovics K, Máthé C. Beyer D, et al. Among authors: jambrovics k. Ann Bot. 2012 Sep;110(4):797-808. doi: 10.1093/aob/mcs154. Epub 2012 Jul 20. Ann Bot. 2012. PMID: 22819947 Free PMC article.