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2020 | 1 |
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Arginase 1/2 Inhibitor OATD-02: From Discovery to First-in-man Setup in Cancer Immunotherapy.
Mol Cancer Ther. 2023 Jul 5;22(7):807-817. doi: 10.1158/1535-7163.MCT-22-0721.
Mol Cancer Ther. 2023.
PMID: 36939275
OATD-02 Validates the Benefits of Pharmacological Inhibition of Arginase 1 and 2 in Cancer.
Grzybowski MM, Stańczak PS, Pomper P, Błaszczyk R, Borek B, Gzik A, Nowicka J, Jędrzejczak K, Brzezińska J, Rejczak T, Güner-Chalimoniuk NC, Kikulska A, Mlącki M, Pęczkowicz-Szyszka J, Olczak J, Gołębiowski A, Dzwonek K, Dobrzański P, Zasłona Z.
Grzybowski MM, et al. Among authors: nowicka j.
Cancers (Basel). 2022 Aug 17;14(16):3967. doi: 10.3390/cancers14163967.
Cancers (Basel). 2022.
PMID: 36010962
Free PMC article.
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Discovery and Pharmacokinetics of Sulfamides and Guanidines as Potent Human Arginase 1 Inhibitors.
Blaszczyk R, Brzezinska J, Dymek B, Stanczak PS, Mazurkiewicz M, Olczak J, Nowicka J, Dzwonek K, Zagozdzon A, Golab J, Golebiowski A.
Blaszczyk R, et al. Among authors: nowicka j.
ACS Med Chem Lett. 2020 Mar 13;11(4):433-438. doi: 10.1021/acsmedchemlett.9b00508. eCollection 2020 Apr 9.
ACS Med Chem Lett. 2020.
PMID: 32292546
Free PMC article.
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Novel orally bioavailable piperidine derivatives as extracellular arginase inhibitors developed by a ring expansion.
Gzik A, Borek B, Chrzanowski J, Jedrzejczak K, Dziegielewski M, Brzezinska J, Nowicka J, Grzybowski MM, Rejczak T, Niedzialek D, Wieczorek G, Olczak J, Golebiowski A, Zaslona Z, Blaszczyk R.
Gzik A, et al. Among authors: nowicka j.
Eur J Med Chem. 2024 Jan 15;264:116033. doi: 10.1016/j.ejmech.2023.116033. Epub 2023 Dec 10.
Eur J Med Chem. 2024.
PMID: 38096651
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