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Page 1
Schistosome sirtuins as drug targets.
Lancelot J, Cabezas-Cruz A, Caby S, Marek M, Schultz J, Romier C, Sippl W, Jung M, Pierce RJ. Lancelot J, et al. Future Med Chem. 2015;7(6):765-82. doi: 10.4155/fmc.15.24. Future Med Chem. 2015. PMID: 25996069 Free article. Review.
Histone deacetylase 8 interacts with the GTPase SmRho1 in Schistosoma mansoni.
Pagliazzo L, Caby S, Lancelot J, Salomé-Desnoulez S, Saliou JM, Heimburg T, Chassat T, Cailliau K, Sippl W, Vicogne J, Pierce RJ. Pagliazzo L, et al. Among authors: lancelot j. PLoS Negl Trop Dis. 2021 Nov 29;15(11):e0009503. doi: 10.1371/journal.pntd.0009503. eCollection 2021 Nov. PLoS Negl Trop Dis. 2021. PMID: 34843489 Free PMC article.
Analysis of the interactome of Schistosoma mansoni histone deacetylase 8.
Caby S, Pagliazzo L, Lancelot J, Saliou JM, Bertheaume N, Pierce RJ, Roger E. Caby S, et al. Among authors: lancelot j. PLoS Negl Trop Dis. 2017 Nov 20;11(11):e0006089. doi: 10.1371/journal.pntd.0006089. eCollection 2017 Nov. PLoS Negl Trop Dis. 2017. PMID: 29155817 Free PMC article.
Synthesis, structure-activity relationships, cocrystallization and cellular characterization of novel smHDAC8 inhibitors for the treatment of schistosomiasis.
Ghazy E, Heimburg T, Lancelot J, Zeyen P, Schmidtkunz K, Truhn A, Darwish S, Simoben CV, Shaik TB, Erdmann F, Schmidt M, Robaa D, Romier C, Jung M, Pierce R, Sippl W. Ghazy E, et al. Among authors: lancelot j. Eur J Med Chem. 2021 Dec 5;225:113745. doi: 10.1016/j.ejmech.2021.113745. Epub 2021 Aug 8. Eur J Med Chem. 2021. PMID: 34392190
Characterization of Histone Deacetylase 8 (HDAC8) Selective Inhibition Reveals Specific Active Site Structural and Functional Determinants.
Marek M, Shaik TB, Heimburg T, Chakrabarti A, Lancelot J, Ramos-Morales E, Da Veiga C, Kalinin D, Melesina J, Robaa D, Schmidtkunz K, Suzuki T, Holl R, Ennifar E, Pierce RJ, Jung M, Sippl W, Romier C. Marek M, et al. Among authors: lancelot j. J Med Chem. 2018 Nov 21;61(22):10000-10016. doi: 10.1021/acs.jmedchem.8b01087. Epub 2018 Nov 8. J Med Chem. 2018. PMID: 30347148 Free article.
24 results