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Development of Novel Pyridine-Thiazole Hybrid Molecules as Potential Anticancer Agents.
Ivasechko I, Yushyn I, Roszczenko P, Senkiv J, Finiuk N, Lesyk D, Holota S, Czarnomysy R, Klyuchivska O, Khyluk D, Kashchak N, Gzella A, Bielawski K, Bielawska A, Stoika R, Lesyk R. Ivasechko I, et al. Among authors: senkiv j. Molecules. 2022 Sep 21;27(19):6219. doi: 10.3390/molecules27196219. Molecules. 2022. PMID: 36234755 Free PMC article.
1,4-Naphthoquinone Motif in the Synthesis of New Thiopyrano[2,3-d]thiazoles as Potential Biologically Active Compounds.
Lozynskyi A, Senkiv J, Ivasechko I, Finiuk N, Klyuchivska O, Kashchak N, Lesyk D, Karkhut A, Polovkovych S, Levytska O, Karpenko O, Boshkayeva A, Sayakova G, Gzella A, Stoika R, Lesyk R. Lozynskyi A, et al. Among authors: senkiv j. Molecules. 2022 Nov 4;27(21):7575. doi: 10.3390/molecules27217575. Molecules. 2022. PMID: 36364402 Free PMC article.
Molecular design, synthesis and anticancer activity of new thiopyrano[2,3-d]thiazoles based on 5-hydroxy-1,4-naphthoquinone (juglone).
Ivasechko I, Lozynskyi A, Senkiv J, Roszczenko P, Kozak Y, Finiuk N, Klyuchivska O, Kashchak N, Manko N, Maslyak Z, Lesyk D, Karkhut A, Polovkovych S, Czarnomysy R, Szewczyk O, Kozytskiy A, Karpenko O, Khyluk D, Gzella A, Bielawski K, Bielawska A, Dzubak P, Gurska S, Hajduch M, Stoika R, Lesyk R. Ivasechko I, et al. Among authors: senkiv j. Eur J Med Chem. 2023 Apr 5;252:115304. doi: 10.1016/j.ejmech.2023.115304. Epub 2023 Mar 24. Eur J Med Chem. 2023. PMID: 37001390 Free article.
Lipid droplet-mediated scavenging as novel intrinsic and adaptive resistance factor against the multikinase inhibitor ponatinib.
Englinger B, Laemmerer A, Moser P, Kallus S, Röhrl C, Pirker C, Baier D, Mohr T, Niederstaetter L, Meier-Menches SM, Gerner C, Gabler L, Gojo J, Timelthaler G, Senkiv J, Jäger W, Kowol CR, Heffeter P, Berger W. Englinger B, et al. Among authors: senkiv j. Int J Cancer. 2020 Sep 15;147(6):1680-1693. doi: 10.1002/ijc.32924. Epub 2020 Mar 2. Int J Cancer. 2020. PMID: 32064608 Free PMC article.
Intrinsic fluorescence of the clinically approved multikinase inhibitor nintedanib reveals lysosomal sequestration as resistance mechanism in FGFR-driven lung cancer.
Englinger B, Kallus S, Senkiv J, Heilos D, Gabler L, van Schoonhoven S, Terenzi A, Moser P, Pirker C, Timelthaler G, Jäger W, Kowol CR, Heffeter P, Grusch M, Berger W. Englinger B, et al. Among authors: senkiv j. J Exp Clin Cancer Res. 2017 Sep 7;36(1):122. doi: 10.1186/s13046-017-0592-3. J Exp Clin Cancer Res. 2017. PMID: 28882160 Free PMC article.