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Year Number of Results
2017 1
2018 1
2021 2
2022 4
2023 5
2024 1

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14 results

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Page 1
How Carvedilol activates β2-adrenoceptors.
Benkel T, Zimmermann M, Zeiner J, Bravo S, Merten N, Lim VJY, Matthees ESF, Drube J, Miess-Tanneberg E, Malan D, Szpakowska M, Monteleone S, Grimes J, Koszegi Z, Lanoiselée Y, O'Brien S, Pavlaki N, Dobberstein N, Inoue A, Nikolaev V, Calebiro D, Chevigné A, Sasse P, Schulz S, Hoffmann C, Kolb P, Waldhoer M, Simon K, Gomeza J, Kostenis E. Benkel T, et al. Among authors: drube j. Nat Commun. 2022 Nov 19;13(1):7109. doi: 10.1038/s41467-022-34765-w. Nat Commun. 2022. PMID: 36402762 Free PMC article.
Plasma membrane preassociation drives β-arrestin coupling to receptors and activation.
Grimes J, Koszegi Z, Lanoiselée Y, Miljus T, O'Brien SL, Stepniewski TM, Medel-Lacruz B, Baidya M, Makarova M, Mistry R, Goulding J, Drube J, Hoffmann C, Owen DM, Shukla AK, Selent J, Hill SJ, Calebiro D. Grimes J, et al. Among authors: drube j. Cell. 2023 May 11;186(10):2238-2255.e20. doi: 10.1016/j.cell.2023.04.018. Epub 2023 May 4. Cell. 2023. PMID: 37146613 Free PMC article.
Differential Regulation of GPCRs-Are GRK Expression Levels the Key?
Matthees ESF, Haider RS, Hoffmann C, Drube J. Matthees ESF, et al. Among authors: drube j. Front Cell Dev Biol. 2021 May 24;9:687489. doi: 10.3389/fcell.2021.687489. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34109182 Free PMC article. Review.
The expression profile and tumorigenic mechanisms of CD97 (ADGRE5) in glioblastoma render it a targetable vulnerability.
Ravn-Boess N, Roy N, Hattori T, Bready D, Donaldson H, Lawson C, Lapierre C, Korman A, Rodrick T, Liu E, Frenster JD, Stephan G, Wilcox J, Corrado AD, Cai J, Ronnen R, Wang S, Haddock S, Sabio Ortiz J, Mishkit O, Khodadadi-Jamayran A, Tsirigos A, Fenyö D, Zagzag D, Drube J, Hoffmann C, Perna F, Jones DR, Possemato R, Koide A, Koide S, Park CY, Placantonakis DG. Ravn-Boess N, et al. Among authors: drube j. Cell Rep. 2023 Nov 28;42(11):113374. doi: 10.1016/j.celrep.2023.113374. Epub 2023 Nov 8. Cell Rep. 2023. PMID: 37938973 Free PMC article.
G Protein-Coupled Receptor Kinase 2 Selectively Enhances β-Arrestin Recruitment to the D2 Dopamine Receptor through Mechanisms That Are Independent of Receptor Phosphorylation.
Sánchez-Soto M, Boldizsar NM, Schardien KA, Madaras NS, Willette BKA, Inbody LR, Dasaro C, Moritz AE, Drube J, Haider RS, Free RB, Hoffman C, Sibley DR. Sánchez-Soto M, et al. Among authors: drube j. Biomolecules. 2023 Oct 20;13(10):1552. doi: 10.3390/biom13101552. Biomolecules. 2023. PMID: 37892234 Free PMC article.
A bead-based GPCR phosphorylation immunoassay for high-throughput ligand profiling and GRK inhibitor screening.
Kaufmann J, Blum NK, Nagel F, Schuler A, Drube J, Degenhart C, Engel J, Eickhoff JE, Dasgupta P, Fritzwanker S, Guastadisegni M, Schulte C, Miess-Tanneberg E, Maric HM, Spetea M, Kliewer A, Baumann M, Klebl B, Reinscheid RK, Hoffmann C, Schulz S. Kaufmann J, et al. Among authors: drube j. Commun Biol. 2022 Nov 9;5(1):1206. doi: 10.1038/s42003-022-04135-9. Commun Biol. 2022. PMID: 36352263 Free PMC article.
The Neurobeachin-like 2 Protein Regulates Mast Cell Homeostasis.
Drube S, Grimlowski R, Deppermann C, Fröbel J, Kraft F, Andreas N, Stegner D, Dudeck J, Weber F, Rödiger M, Göpfert C, Drube J, Reich D, Nieswandt B, Dudeck A, Kamradt T. Drube S, et al. Among authors: drube j. J Immunol. 2017 Oct 15;199(8):2948-2957. doi: 10.4049/jimmunol.1700556. Epub 2017 Sep 8. J Immunol. 2017. PMID: 28887433
14 results