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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 1
2003 1
2005 2
2006 1
2007 3
2008 8
2009 6
2010 4
2011 1
2012 3
2013 4
2014 4
2015 8
2016 9
2017 3
2018 9
2019 5
2020 11
2021 7
2022 6
2023 7
2024 1

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93 results

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Page 1
The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer.
Vervoort SJ, Welsh SA, Devlin JR, Barbieri E, Knight DA, Offley S, Bjelosevic S, Costacurta M, Todorovski I, Kearney CJ, Sandow JJ, Fan Z, Blyth B, McLeod V, Vissers JHA, Pavic K, Martin BP, Gregory G, Demosthenous E, Zethoven M, Kong IY, Hawkins ED, Hogg SJ, Kelly MJ, Newbold A, Simpson KJ, Kauko O, Harvey KF, Ohlmeyer M, Westermarck J, Gray N, Gardini A, Johnstone RW. Vervoort SJ, et al. Among authors: westermarck j. Cell. 2021 Jun 10;184(12):3143-3162.e32. doi: 10.1016/j.cell.2021.04.022. Epub 2021 May 17. Cell. 2021. PMID: 34004147 Free PMC article.
Druggable cancer phosphatases.
Vainonen JP, Momeny M, Westermarck J. Vainonen JP, et al. Among authors: westermarck j. Sci Transl Med. 2021 Apr 7;13(588):eabe2967. doi: 10.1126/scitranslmed.abe2967. Sci Transl Med. 2021. PMID: 33827975 Review.
PP2A inhibition is a druggable MEK inhibitor resistance mechanism in KRAS-mutant lung cancer cells.
Kauko O, O'Connor CM, Kulesskiy E, Sangodkar J, Aakula A, Izadmehr S, Yetukuri L, Yadav B, Padzik A, Laajala TD, Haapaniemi P, Momeny M, Varila T, Ohlmeyer M, Aittokallio T, Wennerberg K, Narla G, Westermarck J. Kauko O, et al. Among authors: westermarck j. Sci Transl Med. 2018 Jul 18;10(450):eaaq1093. doi: 10.1126/scitranslmed.aaq1093. Sci Transl Med. 2018. PMID: 30021885 Free PMC article.
Cancer stem cell phosphatases.
Momeny M, Arsiola T, Westermarck J. Momeny M, et al. Among authors: westermarck j. Biochem J. 2021 Jul 30;478(14):2899-2920. doi: 10.1042/BCJ20210254. Biochem J. 2021. PMID: 34319405 Review.
Structural mechanism for inhibition of PP2A-B56α and oncogenicity by CIP2A.
Pavic K, Gupta N, Omella JD, Derua R, Aakula A, Huhtaniemi R, Määttä JA, Höfflin N, Okkeri J, Wang Z, Kauko O, Varjus R, Honkanen H, Abankwa D, Köhn M, Hytönen VP, Xu W, Nilsson J, Page R, Janssens V, Leitner A, Westermarck J. Pavic K, et al. Among authors: westermarck j. Nat Commun. 2023 Feb 28;14(1):1143. doi: 10.1038/s41467-023-36693-9. Nat Commun. 2023. PMID: 36854761 Free PMC article.
Endogenous PP2A inhibitor CIP2A degradation by chaperone-mediated autophagy contributes to the antitumor effect of mitochondrial complex I inhibition.
Cazzoli R, Romeo F, Pallavicini I, Peri S, Romanenghi M, Pérez-Valencia JA, Hagag E, Ferrucci F, Elgendy M, Vittorio O, Pece S, Foiani M, Westermarck J, Minucci S. Cazzoli R, et al. Among authors: westermarck j. Cell Rep. 2023 Jun 27;42(6):112616. doi: 10.1016/j.celrep.2023.112616. Epub 2023 Jun 7. Cell Rep. 2023. PMID: 37289585 Free article.
RAS and PP2A activities converge on epigenetic gene regulation.
Aakula A, Sharma M, Tabaro F, Nätkin R, Kamila J, Honkanen H, Schapira M, Arrowsmith C, Nykter M, Westermarck J. Aakula A, et al. Among authors: westermarck j. Life Sci Alliance. 2023 Mar 1;6(5):e202301928. doi: 10.26508/lsa.202301928. Print 2023 May. Life Sci Alliance. 2023. PMID: 36858798 Free PMC article.
93 results