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Nirmatrelvir-resistant SARS-CoV-2 variants with high fitness in an infectious cell culture system.
Zhou Y, Gammeltoft KA, Ryberg LA, Pham LV, Tjørnelund HD, Binderup A, Duarte Hernandez CR, Fernandez-Antunez C, Offersgaard A, Fahnøe U, Peters GHJ, Ramirez S, Bukh J, Gottwein JM. Zhou Y, et al. Among authors: gottwein jm. Sci Adv. 2022 Dec 21;8(51):eadd7197. doi: 10.1126/sciadv.add7197. Epub 2022 Dec 21. Sci Adv. 2022. PMID: 36542720 Free PMC article.
Evolutionary Pathways to Persistence of Highly Fit and Resistant Hepatitis C Virus Protease Inhibitor Escape Variants.
Jensen SB, Fahnøe U, Pham LV, Serre SBN, Tang Q, Ghanem L, Pedersen MS, Ramirez S, Humes D, Pihl AF, Filskov J, Sølund CS, Dietz J, Fourati S, Pawlotsky JM, Sarrazin C, Weis N, Schønning K, Krarup H, Bukh J, Gottwein JM. Jensen SB, et al. Among authors: gottwein jm. Hepatology. 2019 Sep;70(3):771-787. doi: 10.1002/hep.30647. Epub 2019 Jun 5. Hepatology. 2019. PMID: 30964552 Free PMC article. Review.
SARS-CoV-2 Production in a Scalable High Cell Density Bioreactor.
Offersgaard A, Duarte Hernandez CR, Pihl AF, Costa R, Venkatesan NP, Lin X, Van Pham L, Feng S, Fahnøe U, Scheel TKH, Ramirez S, Reichl U, Bukh J, Genzel Y, Gottwein JM. Offersgaard A, et al. Among authors: gottwein jm. Vaccines (Basel). 2021 Jun 29;9(7):706. doi: 10.3390/vaccines9070706. Vaccines (Basel). 2021. PMID: 34209694 Free PMC article.
An inactivated SARS-CoV-2 vaccine induced cross-neutralizing persisting antibodies and protected against challenge in small animals.
Offersgaard A, Duarte Hernandez CR, Feng S, Marichal-Gallardo P, Holmbeck K, Pihl AF, Fernandez-Antunez C, Alzua GP, Hartmann KT, Pham LV, Zhou Y, Gammeltoft KA, Fahnøe U, Schneider UV, Pedersen GK, Jensen HE, Christensen JP, Ramirez S, Bukh J, Gottwein JM. Offersgaard A, et al. Among authors: gottwein jm. iScience. 2023 Feb 17;26(2):105949. doi: 10.1016/j.isci.2023.105949. Epub 2023 Jan 10. iScience. 2023. PMID: 36644321 Free PMC article.
Specific Antibodies Induced by Immunization with Hepatitis B Virus-Like Particles Carrying Hepatitis C Virus Envelope Glycoprotein 2 Epitopes Show Differential Neutralization Efficiency.
Czarnota A, Offersgaard A, Pihl AF, Prentoe J, Bukh J, Gottwein JM, Bieńkowska-Szewczyk K, Grzyb K. Czarnota A, et al. Among authors: gottwein jm. Vaccines (Basel). 2020 Jun 10;8(2):294. doi: 10.3390/vaccines8020294. Vaccines (Basel). 2020. PMID: 32532076 Free PMC article.