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Effects of pre-operative isolation on postoperative pulmonary complications after elective surgery: an international prospective cohort study.
COVIDSurg Collaborative; GlobalSurg Collaborative. COVIDSurg Collaborative, et al. Anaesthesia. 2021 Nov;76(11):1454-1464. doi: 10.1111/anae.15560. Epub 2021 Aug 9. Anaesthesia. 2021. PMID: 34371522 Free article. Clinical Trial.
Although the overall rates of postoperative pulmonary complications were similar in those that isolated and those that did not (2.1% vs 2.0%, respectively), isolation was associated with higher rates of postoperative pulmonary complications after adjustment (adjusted OR 1.20, 95% …
Although the overall rates of postoperative pulmonary complications were similar in those that isolated and those that did not (2.1% vs 2.0% …
Evaluation of a quality improvement intervention to reduce anastomotic leak following right colectomy (EAGLE): pragmatic, batched stepped-wedge, cluster-randomized trial in 64 countries.
ESCP EAGLE Safe Anastomosis Collaborative and NIHR Global Health Research Unit in Surgery. ESCP EAGLE Safe Anastomosis Collaborative and NIHR Global Health Research Unit in Surgery. Br J Surg. 2024 Jan 3;111(1):znad370. doi: 10.1093/bjs/znad370. Br J Surg. 2024. PMID: 38029386 Free PMC article. Clinical Trial.
The primary analysis included 3039 of the 3268 patients recruited (206 patients had no anastomosis and 23 were lost to follow-up), with anastomotic leaks arising before and after the intervention in 10.1 and 9.6 per cent respectively (adjusted OR 0.87, 95 per cent c.i. 0.59 to 1. …
The primary analysis included 3039 of the 3268 patients recruited (206 patients had no anastomosis and 23 were lost to follow-up), with anas …
Cognitive impairment and dementia in young onset Parkinson's disease.
Santos-García D, de Deus Fonticoba T, Cores Bartolomé C, Feal Painceiras MJ, García Díaz I, Íñiguez Alvarado MC, Paz JM, Jesús S, Cosgaya M, García Caldentey J, Caballol N, Legarda I, Hernández Vara J, Cabo I, López Manzanares L, González Aramburu I, Ávila Rivera MA, Gómez Mayordomo V, Nogueira V, Dotor García-Soto J, Borrué C, Solano Vila B, Álvarez Sauco M, Vela L, Escalante S, Cubo E, Mendoza Z, Martínez Castrillo JC, Sánchez Alonso P, Alonso Losada MG, López Ariztegui N, Gastón I, Kulisevsky J, Seijo M, Valero C, Alonso Redondo R, Buongiorno MT, Ordás C, Menéndez-González M, McAfee D, Martinez-Martin P, Mir P; COPPADIS Study Group. Santos-García D, et al. J Neurol. 2023 Dec;270(12):5793-5812. doi: 10.1007/s00415-023-11921-w. Epub 2023 Aug 14. J Neurol. 2023. PMID: 37578489

The score on the PD-CRS and its subscore domains was higher at all visits in YOPD compared to non-YOPD patients and to controls (p < 0.0001 in all analysis), but no differences were detected between YOPD patients and controls. Only non-YOPD patients had significant impa

The score on the PD-CRS and its subscore domains was higher at all visits in YOPD compared to non-YOPD patients and to controls (p &l …
Impact of Intermediate Susceptibility to Penicillin on Antimicrobial Treatment and Outcomes of Endocarditis Caused by Viridans and Gallolyticus Group Streptococci.
Escrihuela-Vidal F, Berbel D, Fernández-Hidalgo N, Escolà-Vergé L, Muñoz P, Olmedo M, Goenaga MÁ, Goikoetxea J, Fariñas MC, De Alarcón A, Miró JM, Ojeda G, Plata A, Cuervo G, Carratalà J; GAMES Investigators. Escrihuela-Vidal F, et al. Clin Infect Dis. 2023 Nov 11;77(9):1273-1281. doi: 10.1093/cid/ciad375. Clin Infect Dis. 2023. PMID: 37345869
Heart failure (odds ratio [OR]: 6.06; 95% confidence interval [CI]: 1.37-26.87; P = .018), central nervous system emboli (OR: 9.83; 95% CI: 2.17-44.49; P = .003) and intracardiac abscess (OR: 13.47; 95% CI: 2.24-81.08; P = .004) were independently associated …
Heart failure (odds ratio [OR]: 6.06; 95% confidence interval [CI]: 1.37-26.87; P = .018), central nervous system emboli (OR: 9.83; 9 …
Giant Non-Functioning Pituitary Adenoma: Clinical Characteristics and Therapeutic Outcomes.
Iglesias P, Arcano K, Triviño V, Guerrero-Pérez F, Rodríguez Berrocal V, Vior C, Cordido F, Villabona C, Díez JJ. Iglesias P, et al. Exp Clin Endocrinol Diabetes. 2021 Mar;129(4):309-313. doi: 10.1055/a-1017-3288. Epub 2020 Jan 2. Exp Clin Endocrinol Diabetes. 2021. PMID: 31896156
Women had larger tumors [4.8 cm (4.2-5.4) vs. 4.5 cm (4.0-4.9); p=0.048]. Hypopituitarism [partial (n=22, 55%) or complete (n=9, 22.5%)] at diagnosis was present in 77.5% of the patients. ...Hypopituitarism rate was similar (75.0%), although with significant changes (p
Women had larger tumors [4.8 cm (4.2-5.4) vs. 4.5 cm (4.0-4.9); p=0.048]. Hypopituitarism [partial (n=22, 55%) or complete (n=9, 22.5 …
Prognostic factors in patients with vulvar cancer: the VULCAN study.
Zapardiel I, Iacoponi S, Coronado PJ, Zalewski K, Chen F, Fotopoulou C, Dursun P, Kotsopoulos IC, Jach R, Buda A, Martinez-Serrano MJ, Grimm C, Fruscio R, Garcia E, Sznurkowski JJ, Ruiz C, Noya MC, Barazi D, Diez J, Diaz De la Noval B, Bartusevicius A, De Iaco P, Otero M, Diaz M, Haidopoulos D, Franco S, Blecharz P, Zuñiga MA, Rubio P, Gardella B, Papatheodorou DC, Yildirim Y, Fargas F, Macuks R; VULCAN Study coinvestigators. Zapardiel I, et al. Int J Gynecol Cancer. 2020 Sep;30(9):1285-1291. doi: 10.1136/ijgc-2019-000526. Epub 2020 Jun 22. Int J Gynecol Cancer. 2020. PMID: 32571891
RESULTS: After excluding patients due to incomplete data entry, 1727 patients treated for vulvar cancer between January 2001 and December 2005 were registered for analysis (1535 squamous, 42 melanomas, 38 Paget's disease and 112 other histologic types). Melanomas had the worse pr …
RESULTS: After excluding patients due to incomplete data entry, 1727 patients treated for vulvar cancer between January 2001 and December 20 …
Consequences of canceling elective invasive cardiac procedures during Covid-19 outbreak.
Moreno R, Díez JL, Diarte JA, Macaya F, de la Torrre Hernández JM, Rodríguez-Leor O, Trillo R, Alonso-Briales J, Amat-Santos I, Romaguera R, Díaz JF, Vaquerizo B, Ojeda S, Cruz-González I, Morena-Salas D, Pérez de Prado A, Sarnago F, Portero P, Gutierrez-Barrios A, Alfonso F, Bosch E, Pinar E, Ruiz-Arroyo JR, Ruiz-Quevedo V, Jiménez-Mazuecos J, Lozano F, Rumoroso JR, Novo E, Irazusta FJ, García Del Blanco B, Moreu J, Ballesteros-Pradas SM, Frutos A, Villa M, Alegría-Barrero E, Lázaro R, Paredes E. Moreno R, et al. Catheter Cardiovasc Interv. 2021 Apr 1;97(5):927-937. doi: 10.1002/ccd.29433. Epub 2020 Dec 17. Catheter Cardiovasc Interv. 2021. PMID: 33336506 Free article.

Mortality was significantly higher in patients pending on structural procedures (4.5% vs. 0.8%, respectively; p < .001), in those >80 year-old (5.1% vs. 0.7%, p < .001), and in presence of diabetes (2.7% vs. 0.9%, p = .001), hypertension (2.0% vs. 0.

Mortality was significantly higher in patients pending on structural procedures (4.5% vs. 0.8%, respectively; p < .001), in those

Plasmodium falciparum immunodominant IgG epitopes in subclinical malaria.
Azcárate IG, Marín-García P, Abad P, Pérez-Benavente S, Paz-Artal E, Reche PA, Fobil JN, Rubio JM, Diez A, Puyet A, Bautista JM. Azcárate IG, et al. Sci Rep. 2020 Jun 10;10(1):9398. doi: 10.1038/s41598-020-66384-0. Sci Rep. 2020. PMID: 32523082 Free PMC article.
Although blood-stage Plasmodium falciparum rapidly elicits IgG responses, the target antigens of partially protective and non-protective IgG antibodies as well as the basis for the acquisition of these antibodies remain largely unknown. We performed IgG-immunomics to screen for …
Although blood-stage Plasmodium falciparum rapidly elicits IgG responses, the target antigens of partially protective and non-protective IgG …
Diverticulitis with abscess formation: Outcomes of non-operative management and nomogram for predicting emergency surgery: The Diplicab Study Collaborative Group.
Ocaña J, García-Pérez JC, Fernández-Martínez D, Aguirre I, Pascual I, Lora P, Espin E, Labalde-Martínez M, León C, Pastor-Peinado P, López-Domínguez C, Muñoz-Plaza N, Valle A, Dujovne P, Alías D, Pérez-Santiago L, Correa A, Carmona M, Díez MM, Timoteo A, Salvans S, Medina RE, Gómez T, Fernández-Vega L, Peña E, García-González JM, Blanco-Antona F, Fábregues AI, Sagarra E, Viejo E, Moreno A, Fernández-Cebrián JM, Die J; DIPLICAB Study Collaborative Group. Ocaña J, et al. Surgery. 2023 Sep;174(3):492-501. doi: 10.1016/j.surg.2023.05.016. Epub 2023 Jun 27. Surgery. 2023. PMID: 37385866
Percutaneous drainage (208 patients) was associated with a lower risk of emergency surgery in patients with abscesses of 5 cm (19.9% vs 29.3%, P = .035; odds ratio 0.59 [0.37-0.96]). The multivariate analysis showed that immunosuppression treatment, C-reactive protein (odd …
Percutaneous drainage (208 patients) was associated with a lower risk of emergency surgery in patients with abscesses of 5 cm (19.9% vs 29.3 …
Anandamide-nanoformulation obtained by electrospraying for cardiovascular therapy.
Martín Giménez VM, Díaz-Rodríguez P, Sanz RL, Vivero-Lopez M, Concheiro A, Diez E, Prado N, Enrique Kassuha D, Alvarez-Lorenzo C, Manucha W. Martín Giménez VM, et al. Int J Pharm. 2019 Jul 20;566:1-10. doi: 10.1016/j.ijpharm.2019.05.047. Epub 2019 May 18. Int J Pharm. 2019. PMID: 31112795

In SHR, the treatment with AEA/PCL/PF127 NPs reversed all altered cardiovascular markers and parameters (p < 0.05). Overall, nanoformulated AEA obtained by electrospraying proved to be effective for the treatment of hypertension and its comorbidities, especially cardiov

In SHR, the treatment with AEA/PCL/PF127 NPs reversed all altered cardiovascular markers and parameters (p < 0.05). Overall, nanof

74 results