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Synthesis, in vitro, in silico and in vivo hypoglycemic and lipid-lowering effects of 4-benzyloxy-5-benzylidene-1,3-thiazolidine-2,4-diones mediated by dual PPAR α/γ modulation.
Madrigal-Angulo JL, Ménez-Guerrero C, Estrada-Soto S, Ramírez-Espinosa JJ, Almanza-Pérez JC, León-Rivera I, Hernández-Núñez E, Aguirre-Vidal Y, Flores-León CD, Aguayo-Ortíz R, Navarrete-Vazquez G. Madrigal-Angulo JL, et al. Among authors: ramirez espinosa jj. Bioorg Med Chem Lett. 2022 Aug 15;70:128804. doi: 10.1016/j.bmcl.2022.128804. Epub 2022 May 19. Bioorg Med Chem Lett. 2022. PMID: 35598791
Ursolic acid derivatives as potential antidiabetic agents: In vitro, in vivo, and in silico studies.
Guzmán-Ávila R, Flores-Morales V, Paoli P, Camici G, Ramírez-Espinosa JJ, Cerón-Romero L, Navarrete-Vázquez G, Hidalgo-Figueroa S, Yolanda Rios M, Villalobos-Molina R, Estrada-Soto S. Guzmán-Ávila R, et al. Among authors: ramirez espinosa jj. Drug Dev Res. 2018 Mar;79(2):70-80. doi: 10.1002/ddr.21422. Epub 2018 Jan 29. Drug Dev Res. 2018. PMID: 29380400
Synthesis, in vitro and in silico studies of a PPARγ and GLUT-4 modulator with hypoglycemic effect.
Navarrete-Vázquez G, Torres-Gómez H, Hidalgo-Figueroa S, Ramírez-Espinosa JJ, Estrada-Soto S, Medina-Franco JL, León-Rivera I, Alarcón-Aguilar FJ, Almanza-Pérez JC. Navarrete-Vázquez G, et al. Among authors: ramirez espinosa jj. Bioorg Med Chem Lett. 2014 Sep 15;24(18):4575-4579. doi: 10.1016/j.bmcl.2014.07.068. Epub 2014 Aug 1. Bioorg Med Chem Lett. 2014. PMID: 25131539
1,5-Diarylpyrazole and vanillin hybrids: Synthesis, biological activity and DFT studies.
Hernández-Vázquez E, Castañeda-Arriaga R, Ramírez-Espinosa JJ, Medina-Campos ON, Hernández-Luis F, Chaverri JP, Estrada-Soto S. Hernández-Vázquez E, et al. Among authors: ramirez espinosa jj. Eur J Med Chem. 2015 Jul 15;100:106-18. doi: 10.1016/j.ejmech.2015.06.010. Epub 2015 Jun 5. Eur J Med Chem. 2015. PMID: 26079087
Synthesis and evaluation of thiazolidine-2,4-dione/benzazole derivatives as inhibitors of protein tyrosine phosphatase 1B (PTP-1B): Antihyperglycemic activity with molecular docking study.
Hidalgo-Figueroa S, Estrada-Soto S, Ramírez-Espinosa JJ, Paoli P, Lori G, León-Rivera I, Navarrete-Vázquez G. Hidalgo-Figueroa S, et al. Among authors: ramirez espinosa jj. Biomed Pharmacother. 2018 Nov;107:1302-1310. doi: 10.1016/j.biopha.2018.08.124. Epub 2018 Aug 29. Biomed Pharmacother. 2018. PMID: 30257345
Synthesis and molecular docking of N'-arylidene-5-(4-chlorophenyl)-1-(3,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carbohydrazides as novel hypoglycemic and antioxidant dual agents.
Hernández-Vázquez E, Salgado-Barrera S, Ramírez-Espinosa JJ, Estrada-Soto S, Hernández-Luis F. Hernández-Vázquez E, et al. Among authors: ramirez espinosa jj. Bioorg Med Chem. 2016 May 15;24(10):2298-306. doi: 10.1016/j.bmc.2016.04.007. Epub 2016 Apr 2. Bioorg Med Chem. 2016. PMID: 27079123
13 results