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Nicotinic Antagonist UFR2709 Inhibits Nicotine Reward and Decreases Anxiety in Zebrafish.
Viscarra F, González-Gutierrez J, Esparza E, Figueroa C, Paillali P, Hödar-Salazar M, Cespedes C, Quiroz G, Sotomayor-Zárate R, Reyes-Parada M, Bermúdez I, Iturriaga-Vásquez P. Viscarra F, et al. Among authors: gonzalez gutierrez j. Molecules. 2020 Jun 30;25(13):2998. doi: 10.3390/molecules25132998. Molecules. 2020. PMID: 32630020 Free PMC article.
UFR2709, an Antagonist of Nicotinic Acetylcholine Receptors, Delays the Acquisition and Reduces Long-Term Ethanol Intake in Alcohol-Preferring UChB Bibulous Rats.
Gálvez G, González-Gutiérrez JP, Hödar-Salazar M, Sotomayor-Zárate R, Quintanilla ME, Quilaqueo ME, Rivera-Meza M, Iturriaga-Vásquez P. Gálvez G, et al. Among authors: gonzalez gutierrez jp. Biomedicines. 2022 Jun 22;10(7):1482. doi: 10.3390/biomedicines10071482. Biomedicines. 2022. PMID: 35884787 Free PMC article.
UFR2709, a Nicotinic Acetylcholine Receptor Antagonist, Decreases Ethanol Intake in Alcohol-Preferring Rats.
Quiroz G, Sotomayor-Zárate R, González-Gutierrez JP, Vizcarra F, Moraga F, Bermudez I, Reyes-Parada M, Quintanilla ME, Lagos D, Rivera-Meza M, Iturriaga-Vásquez P. Quiroz G, et al. Among authors: gonzalez gutierrez jp. Front Pharmacol. 2019 Dec 3;10:1429. doi: 10.3389/fphar.2019.01429. eCollection 2019. Front Pharmacol. 2019. PMID: 31849674 Free PMC article.
Neonicotinic analogues: selective antagonists for α4β2 nicotinic acetylcholine receptors.
Faundez-Parraguez M, Farias-Rabelo N, Gonzalez-Gutierrez JP, Etcheverry-Berrios A, Alzate-Morales J, Adasme-Carreño F, Varas R, Bermudez I, Iturriaga-Vasquez P. Faundez-Parraguez M, et al. Among authors: gonzalez gutierrez jp. Bioorg Med Chem. 2013 May 15;21(10):2687-94. doi: 10.1016/j.bmc.2013.03.024. Epub 2013 Mar 26. Bioorg Med Chem. 2013. PMID: 23561269
Synthesis of Novel Nicotinic Ligands with Multimodal Action: Targeting Acetylcholine α4β2, Dopamine and Serotonin Transporters.
González-Gutiérrez JP, Pessoa-Mahana HA, Iturriaga-Vásquez PE, Reyes-Parada MI, Guerra-Díaz NE, Hodar-Salazar M, Viscarra F, Paillali P, Núñez-Vivanco G, Lorca-Carvajal MA, Mella-Raipán J, Zúñiga MC. González-Gutiérrez JP, et al. Molecules. 2019 Oct 22;24(20):3808. doi: 10.3390/molecules24203808. Molecules. 2019. PMID: 31652614 Free PMC article.