Polyfunctionalized α-Phenyl-tert-butyl(benzyl)nitrones: Multifunctional Antioxidants for Stroke Treatment.
Diez-Iriepa D, Knez D, Gobec S, Iriepa I, de Los Ríos C, Bravo I, López-Muñoz F, Marco-Contelles J, Hadjipavlou-Litina D.
Diez-Iriepa D, et al.
Antioxidants (Basel). 2022 Aug 31;11(9):1735. doi: 10.3390/antiox11091735.
Antioxidants (Basel). 2022.
PMID: 36139811
Free PMC article.
As a result, (Z)-N-benzyl-1-(2-(3-(piperidin-1-yl)propoxy)phenyl)methanimine oxide (5) was found to be one of the most potent antioxidants, with high ABTS(+) scavenging activity (19%), and potent lipoxygenase inhibitory capacity (IC(50) = 10 M), selectively inhibiting buty …
As a result, (Z)-N-benzyl-1-(2-(3-(piperidin-1-yl)propoxy)phenyl)methanimine oxide (5) was found to be one of the most potent antioxidants, …