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Sialic acids in pancreatic cancer cells drive tumour-associated macrophage differentiation via the Siglec receptors Siglec-7 and Siglec-9.
Rodriguez E, Boelaars K, Brown K, Eveline Li RJ, Kruijssen L, Bruijns SCM, van Ee T, Schetters STT, Crommentuijn MHW, van der Horst JC, van Grieken NCT, van Vliet SJ, Kazemier G, Giovannetti E, Garcia-Vallejo JJ, van Kooyk Y. Rodriguez E, et al. Among authors: van der horst jc. Nat Commun. 2021 Feb 24;12(1):1270. doi: 10.1038/s41467-021-21550-4. Nat Commun. 2021. PMID: 33627655 Free PMC article.
MUC1 Glycopeptide Vaccine Modified with a GalNAc Glycocluster Targets the Macrophage Galactose C-type Lectin on Dendritic Cells to Elicit an Improved Humoral Response.
Gabba A, Attariya R, Behren S, Pett C, van der Horst JC, Yurugi H, Yu J, Urschbach M, Sabin J, Birrane G, Schmitt E, van Vliet SJ, Besenius P, Westerlind U, Murphy PV. Gabba A, et al. Among authors: van der horst jc. J Am Chem Soc. 2023 Jun 21;145(24):13027-13037. doi: 10.1021/jacs.2c12843. Epub 2023 Jun 6. J Am Chem Soc. 2023. PMID: 37279388 Free PMC article.
FUT9-Driven Programming of Colon Cancer Cells towards a Stem Cell-Like State.
Blanas A, Zaal A, van der Haar Àvila I, Kempers M, Kruijssen L, de Kok M, Popovic MA, van der Horst JC, J van Vliet S. Blanas A, et al. Among authors: van der horst jc. Cancers (Basel). 2020 Sep 10;12(9):2580. doi: 10.3390/cancers12092580. Cancers (Basel). 2020. PMID: 32927726 Free PMC article.
Identification of a secondary binding site in human macrophage galactose-type lectin by microarray studies: Implications for the molecular recognition of its ligands.
Marcelo F, Supekar N, Corzana F, van der Horst JC, Vuist IM, Live D, Boons GPH, Smith DF, van Vliet SJ. Marcelo F, et al. Among authors: van der horst jc. J Biol Chem. 2019 Jan 25;294(4):1300-1311. doi: 10.1074/jbc.RA118.004957. Epub 2018 Nov 30. J Biol Chem. 2019. PMID: 30504228 Free PMC article.
Macrophage galactose-type lectin (MGL) is induced on M2 microglia and participates in the resolution phase of autoimmune neuroinflammation.
Ilarregui JM, Kooij G, Rodríguez E, van der Pol SMA, Koning N, Kalay H, van der Horst JC, van Vliet SJ, García-Vallejo JJ, de Vries HE, van Kooyk Y. Ilarregui JM, et al. Among authors: van der horst jc. J Neuroinflammation. 2019 Jun 27;16(1):130. doi: 10.1186/s12974-019-1522-4. J Neuroinflammation. 2019. PMID: 31248427 Free PMC article.