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Page 1
Puromycin-sensitive aminopeptidase: an antiviral prodrug activating enzyme.
Tehler U, Nelson CH, Peterson LW, Provoda CJ, Hilfinger JM, Lee KD, McKenna CE, Amidon GL. Tehler U, et al. Among authors: hilfinger jm. Antiviral Res. 2010 Mar;85(3):482-9. doi: 10.1016/j.antiviral.2009.12.003. Epub 2009 Dec 5. Antiviral Res. 2010. PMID: 19969024 Free PMC article.
Tyrosine-based 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine and -adenine ((S)-HPMPC and (S)-HPMPA) prodrugs: synthesis, stability, antiviral activity, and in vivo transport studies.
Zakharova VM, Serpi M, Krylov IS, Peterson LW, Breitenbach JM, Borysko KZ, Drach JC, Collins M, Hilfinger JM, Kashemirov BA, McKenna CE. Zakharova VM, et al. Among authors: hilfinger jm. J Med Chem. 2011 Aug 25;54(16):5680-93. doi: 10.1021/jm2001426. Epub 2011 Aug 3. J Med Chem. 2011. PMID: 21812420 Free PMC article.
Evolution of an amino acid based prodrug approach: stay tuned.
Krylov IS, Kashemirov BA, Hilfinger JM, McKenna CE. Krylov IS, et al. Among authors: hilfinger jm. Mol Pharm. 2013 Feb 4;10(2):445-58. doi: 10.1021/mp300663j. Epub 2013 Jan 22. Mol Pharm. 2013. PMID: 23339402 Free PMC article.
20 results