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Showing results for John A. commit
Your search for John A. Commito retrieved no results
Impaired mitochondrial oxidative metabolism in skeletal progenitor cells leads to musculoskeletal disintegration.
Lin C, Yang Q, Guo D, Xie J, Yang YS, Chaugule S, DeSouza N, Oh WT, Li R, Chen Z, John AA, Qiu Q, Zhu LJ, Greenblatt MB, Ghosh S, Li S, Gao G, Haynes C, Emerson CP, Shim JH. Lin C, et al. Among authors: john aa. Nat Commun. 2022 Nov 11;13(1):6869. doi: 10.1038/s41467-022-34694-8. Nat Commun. 2022. PMID: 36369293 Free PMC article.
Here, we demonstrate a requirement for mitochondrial oxidative phosphorylation in the osteogenic commitment and differentiation of skeletal progenitors. Deletion of Evolutionarily Conserved Signaling Intermediate in Toll pathways (ECSIT) in skeletal progenitors hinders bon …
Here, we demonstrate a requirement for mitochondrial oxidative phosphorylation in the osteogenic commitment and differentiation of sk …
MEPicides: potent antimalarial prodrugs targeting isoprenoid biosynthesis.
Edwards RL, Brothers RC, Wang X, Maron MI, Ziniel PD, Tsang PS, Kraft TE, Hruz PW, Williamson KC, Dowd CS, John ARO. Edwards RL, et al. Among authors: john aro. Sci Rep. 2017 Aug 21;7(1):8400. doi: 10.1038/s41598-017-07159-y. Sci Rep. 2017. PMID: 28827774 Free PMC article.
Notably, environmental isolates resistant to current therapies remained sensitive to RCB-185, the compound effectively treated sexually-committed parasites, and was both safe and efficacious in malaria-infected mice. ...
Notably, environmental isolates resistant to current therapies remained sensitive to RCB-185, the compound effectively treated sexually-c
Effectiveness of Web-Delivered Acceptance and Commitment Therapy in Relation to Mental Health and Well-Being: A Systematic Review and Meta-Analysis.
Brown M, Glendenning A, Hoon AE, John A. Brown M, et al. Among authors: john a. J Med Internet Res. 2016 Aug 24;18(8):e221. doi: 10.2196/jmir.6200. J Med Internet Res. 2016. PMID: 27558740 Free PMC article. Review.
OBJECTIVE: The main aim of this review was to evaluate the evidence base of acceptance and commitment therapy (ACT) in a Web-based delivery format. METHOD: A systematic review of the literature and meta-analysis was conducted. ...
OBJECTIVE: The main aim of this review was to evaluate the evidence base of acceptance and commitment therapy (ACT) in a Web-based de …
Adaptation of ACTivate Your Wellbeing, a Digital Health and Well-being Program for Young Persons: Co-design Approach.
Brown M, Lord E, John A. Brown M, et al. Among authors: john a. JMIR Form Res. 2023 Apr 13;7:e39913. doi: 10.2196/39913. JMIR Form Res. 2023. PMID: 37052994 Free PMC article.
The website includes 5 lifestyle behavior change modules and a 12-week well-being intervention based on acceptance and commitment therapy. It was timely to adapt the resource for a new audience in the wake of the COVID-19 pandemic. ...
The website includes 5 lifestyle behavior change modules and a 12-week well-being intervention based on acceptance and commitment the …
miR-487b-3p impairs osteoblastogenesis by targeting Notch-regulated ankyrin-repeat protein (Nrarp).
John AA, Prakash R, Singh D. John AA, et al. J Endocrinol. 2019 Jun 1;241(3):249-263. doi: 10.1530/JOE-19-0015. J Endocrinol. 2019. PMID: 30978699
It is evident from the ever-growing scientific literature that miRNAs play a significant role in osteoblast commitment and differentiation. Here, we report that overexpression of miR-487b-3p leads to inhibition of osteoblastic differentiation. ...
It is evident from the ever-growing scientific literature that miRNAs play a significant role in osteoblast commitment and differenti …
Nucleotide Imbalance, Provoked by Downregulation of Aspartate Transcarbamoylase Impairs Cold Acclimation in Arabidopsis.
Bellin L, Garza Amaya DL, Scherer V, Pruß T, John A, Richter A, Möhlmann T. Bellin L, et al. Among authors: john a. Molecules. 2023 Feb 7;28(4):1585. doi: 10.3390/molecules28041585. Molecules. 2023. PMID: 36838573 Free PMC article.
Aspartate transcarbamoylase (ATC) catalyzes the first committed step in pyrimidine de novo synthesis. As shown before, mutants with 80% reduced transcript and protein levels exhibit reduced levels of pyrimidine metabolites and thus nucleotide limitation and imbalance. ...
Aspartate transcarbamoylase (ATC) catalyzes the first committed step in pyrimidine de novo synthesis. As shown before, mutants with 8 …
Development of a Web-Based Acceptance and Commitment Therapy Intervention to Support Lifestyle Behavior Change and Well-Being in Health Care Staff: Participatory Design Study.
Brown M, Hooper N, Eslambolchilar P, John A. Brown M, et al. Among authors: john a. JMIR Form Res. 2020 Nov 30;4(11):e22507. doi: 10.2196/22507. JMIR Form Res. 2020. PMID: 33252350 Free PMC article.
A structured, sequential, automated, 12-week, web-based emotional well-being intervention based on acceptance and commitment therapy was developed. Freely navigated psychoeducational resources were also included. ...
A structured, sequential, automated, 12-week, web-based emotional well-being intervention based on acceptance and commitment therapy …
Larvicidal efficacy of Adiantobischrysene from Adiantum latifolium against Oryctes rhinoceros through disrupting metamorphosis and impeding microbial mediated digestion.
Pradeep Kumar R, John A, Kumar P, Dinesh Babu KV, Evans DA. Pradeep Kumar R, et al. Among authors: john a. Pest Manag Sci. 2018 Aug;74(8):1821-1828. doi: 10.1002/ps.4880. Epub 2018 Mar 25. Pest Manag Sci. 2018. PMID: 29393564
An enzyme immunoassay showed a large peak in 20-hydroxyecdysone that commits larvae to precocious metamorphosis. CONCLUSION: This study demonstrated that the antibacterial and metamorphosis disrupting activity of Adiantobischrysene make it a natural pesticidal compound aga …
An enzyme immunoassay showed a large peak in 20-hydroxyecdysone that commits larvae to precocious metamorphosis. CONCLUSION: This stu …
Rimonabant for prevention of cardiovascular events (CRESCENDO): a randomised, multicentre, placebo-controlled trial.
Topol EJ, Bousser MG, Fox KA, Creager MA, Despres JP, Easton JD, Hamm CW, Montalescot G, Steg PG, Pearson TA, Cohen E, Gaudin C, Job B, Murphy JH, Bhatt DL; CRESCENDO Investigators. Topol EJ, et al. Lancet. 2010 Aug 14;376(9740):517-23. doi: 10.1016/S0140-6736(10)60935-X. Lancet. 2010. PMID: 20709233 Clinical Trial.
Four patients in the rimonabant group and one in the placebo group committed suicide. INTERPRETATION: The premature termination of this trial has important lessons for drug development. ...
Four patients in the rimonabant group and one in the placebo group committed suicide. INTERPRETATION: The premature termination of th …
Implementation of Dynamic Lycra® Orthoses for Arm Rehabilitation in the Context of a Randomised Controlled Feasibility Trial in Stroke: A Qualitative study Using Normalisation Process Theory.
Delvaux J, John A, Wedderburn L, Morris J. Delvaux J, et al. Among authors: john a. Rehabil Process Outcome. 2020 Aug 31;9:1179572720950210. doi: 10.1177/1179572720950210. eCollection 2020. Rehabil Process Outcome. 2020. PMID: 34497470 Free PMC article.
RESULTS: Practitioners intuitively made sense of the intervention in the face of uncertainty about its precise mechanisms of action (Normalisation Process Theory construct: coherence) and espoused commitment to the research, despite uncertainty about orthosis effectiveness …
RESULTS: Practitioners intuitively made sense of the intervention in the face of uncertainty about its precise mechanisms of action (Normali …
14 results