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Histamine Activates Human Eosinophils via H2R and H4R Predominantly in Atopic Dermatitis Patients.
Beyer L, Kabatas AS, Mommert S, Stark H, Werfel T, Gutzmer R, Schaper-Gerhardt K. Beyer L, et al. Int J Mol Sci. 2022 Sep 7;23(18):10294. doi: 10.3390/ijms231810294. Int J Mol Sci. 2022. PMID: 36142206 Free PMC article.
In this study, transcriptome analysis of blood eosinophils from AD patients stimulated with histamine and the H(4)R agonist ST-1006 revealed several regulated genes (e.g., IL-18R, IL-1RL1, PDE4B, CXCR4) involved in inflammation. Subsequently, the impact of histamine on one …
In this study, transcriptome analysis of blood eosinophils from AD patients stimulated with histamine and the H(4)R agonist ST-1006 revealed …
Pallidal lead placement in dystonia: leads of non-responders are contained within an anatomical range defined by responders.
Zittel S, Hidding U, Trumpfheller M, Baltzer VL, Gulberti A, Schaper M, Biermann M, Buhmann C, Engel AK, Gerloff C, Westphal M, Stadler J, Köppen JA, Pötter-Nerger M, Moll CKE, Hamel W. Zittel S, et al. J Neurol. 2020 Jun;267(6):1663-1671. doi: 10.1007/s00415-020-09753-z. Epub 2020 Feb 17. J Neurol. 2020. PMID: 32067124 Free PMC article.
Of note, non-responders were also stimulated within the same area. This suggests that factors other than mere lead location (e.g., clinical phenotype, genetic background) have determined clinical outcome in the present cohort....
Of note, non-responders were also stimulated within the same area. This suggests that factors other than mere lead location (e.g., cl …