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Hepatic pyruvate and alanine metabolism are critical and complementary for maintenance of antioxidant capacity and resistance to oxidative insult.
Yiew NKH, Vazquez JH, Martino MR, Kennon-McGill S, Price JR, Allard FD, Yee EU, Layman AJ, James LP, McCommis KS, Finck BN, McGill MR. Yiew NKH, et al. Among authors: vazquez jh. Mol Metab. 2023 Nov;77:101808. doi: 10.1016/j.molmet.2023.101808. Epub 2023 Sep 15. Mol Metab. 2023. PMID: 37716594 Free PMC article.
Short-Term Safety of Repeated Acetaminophen Use in Patients With Compensated Cirrhosis.
McGill MR, James LP, McCullough SS, Moran JH, Mathews SE, Peterson EC, Fleming DP, Tripod ME, Vazquez JH, Kennon-McGill S, Spencer HJ, Dranoff JA. McGill MR, et al. Among authors: vazquez jh. Hepatol Commun. 2022 Feb;6(2):361-373. doi: 10.1002/hep4.1810. Epub 2021 Aug 25. Hepatol Commun. 2022. PMID: 34558847 Free PMC article. Clinical Trial.
Exogenous phosphatidic acid reduces acetaminophen-induced liver injury in mice by activating hepatic interleukin-6 signaling through inter-organ crosstalk.
Clemens MM, Kennon-McGill S, Vazquez JH, Stephens OW, Peterson EA, Johann DJ, Allard FD, Yee EU, McCullough SS, James LP, Finck BN, McGill MR. Clemens MM, et al. Among authors: vazquez jh. Acta Pharm Sin B. 2021 Dec;11(12):3836-3846. doi: 10.1016/j.apsb.2021.08.024. Epub 2021 Aug 26. Acta Pharm Sin B. 2021. PMID: 35024310 Free PMC article.
Paradoxical Patterns of Sinusoidal Obstruction Syndrome-Like Liver Injury in Aged Female CD-1 Mice Triggered by Cannabidiol-Rich Cannabis Extract and Acetaminophen Co-Administration.
Ewing LE, McGill MR, Yee EU, Quick CM, Skinner CM, Kennon-McGill S, Clemens M, Vazquez JH, McCullough SS, Williams DK, Kutanzi KR, Walker LA, ElSohly MA, James LP, Gurley BJ, Koturbash I. Ewing LE, et al. Among authors: vazquez jh. Molecules. 2019 Jun 17;24(12):2256. doi: 10.3390/molecules24122256. Molecules. 2019. PMID: 31212965 Free PMC article.