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Year Number of Results
2002 1
2009 1
2010 2
2011 1
2013 2
2014 2
2016 2
2017 2
2018 3
2019 1
2020 2
2021 1
2023 1
2024 2

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Page 1
COPI vesicle formation and N-myristoylation are targetable vulnerabilities of senescent cells.
McHugh D, Sun B, Gutierrez-Muñoz C, Hernández-González F, Mellone M, Guiho R, Duran I, Pombo J, Pietrocola F, Birch J, Kallemeijn WW, Khadayate S, Dharmalingam G, Vernia S, Tate EW, Martínez-Barbera JP, Withers DJ, Thomas GJ, Serrano M, Gil J. McHugh D, et al. Among authors: pombo j. Nat Cell Biol. 2023 Dec;25(12):1804-1820. doi: 10.1038/s41556-023-01287-6. Epub 2023 Nov 27. Nat Cell Biol. 2023. PMID: 38012402 Free PMC article.
PTBP1-Mediated Alternative Splicing Regulates the Inflammatory Secretome and the Pro-tumorigenic Effects of Senescent Cells.
Georgilis A, Klotz S, Hanley CJ, Herranz N, Weirich B, Morancho B, Leote AC, D'Artista L, Gallage S, Seehawer M, Carroll T, Dharmalingam G, Wee KB, Mellone M, Pombo J, Heide D, Guccione E, Arribas J, Barbosa-Morais NL, Heikenwalder M, Thomas GJ, Zender L, Gil J. Georgilis A, et al. Among authors: pombo j. Cancer Cell. 2018 Jul 9;34(1):85-102.e9. doi: 10.1016/j.ccell.2018.06.007. Cancer Cell. 2018. PMID: 29990503 Free PMC article.
Cardiac glycosides are broad-spectrum senolytics.
Guerrero A, Herranz N, Sun B, Wagner V, Gallage S, Guiho R, Wolter K, Pombo J, Irvine EE, Innes AJ, Birch J, Glegola J, Manshaei S, Heide D, Dharmalingam G, Harbig J, Olona A, Behmoaras J, Dauch D, Uren AG, Zender L, Vernia S, Martínez-Barbera JP, Heikenwalder M, Withers DJ, Gil J. Guerrero A, et al. Among authors: pombo j. Nat Metab. 2019 Nov;1(11):1074-1088. doi: 10.1038/s42255-019-0122-z. Epub 2019 Oct 21. Nat Metab. 2019. PMID: 31799499 Free PMC article.
Detection of senescence using machine learning algorithms based on nuclear features.
Duran I, Pombo J, Sun B, Gallage S, Kudo H, McHugh D, Bousset L, Barragan Avila JE, Forlano R, Manousou P, Heikenwalder M, Withers DJ, Vernia S, Goldin RD, Gil J. Duran I, et al. Among authors: pombo j. Nat Commun. 2024 Feb 3;15(1):1041. doi: 10.1038/s41467-024-45421-w. Nat Commun. 2024. PMID: 38310113 Free PMC article.
XPO7 is a tumor suppressor regulating p21CIP1-dependent senescence.
Innes AJ, Sun B, Wagner V, Brookes S, McHugh D, Pombo J, Porreca RM, Dharmalingam G, Vernia S, Zuber J, Vannier JB, García-Escudero R, Gil J. Innes AJ, et al. Among authors: pombo j. Genes Dev. 2021 Mar 1;35(5-6):379-391. doi: 10.1101/gad.343269.120. Epub 2021 Feb 18. Genes Dev. 2021. PMID: 33602872 Free PMC article.
Maternal obesity alters endoplasmic reticulum homeostasis in offspring pancreas.
Soeda J, Mouralidarane A, Cordero P, Li J, Nguyen V, Carter R, Kapur SR, Pombo J, Poston L, Taylor PD, Vinciguerra M, Oben JA. Soeda J, et al. Among authors: pombo j. J Physiol Biochem. 2016 Jun;72(2):281-91. doi: 10.1007/s13105-016-0476-6. Epub 2016 Mar 15. J Physiol Biochem. 2016. PMID: 26979740 Free PMC article.
Supplementation with a prebiotic (polydextrose) in obese mouse pregnancy improves maternal glucose homeostasis and protects against offspring obesity.
Maragkoudaki X, Naylor M, Papacleovoulou G, Stolarczyk E, Rees D, Pombo JM, Abu-Hayyeh S, Czajka A, Howard JK, Malik AN, Williamson C, Poston L, Taylor PD. Maragkoudaki X, et al. Among authors: pombo jm. Int J Obes (Lond). 2020 Dec;44(12):2382-2393. doi: 10.1038/s41366-020-00682-5. Epub 2020 Oct 8. Int J Obes (Lond). 2020. PMID: 33033395
Central role for melanocortin-4 receptors in offspring hypertension arising from maternal obesity.
Samuelsson AS, Mullier A, Maicas N, Oosterhuis NR, Eun Bae S, Novoselova TV, Chan LF, Pombo JM, Taylor PD, Joles JA, Coen CW, Balthasar N, Poston L. Samuelsson AS, et al. Among authors: pombo jm. Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):12298-12303. doi: 10.1073/pnas.1607464113. Epub 2016 Oct 6. Proc Natl Acad Sci U S A. 2016. PMID: 27791019 Free PMC article.
22 results