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Development of bozepinib-loaded nanocapsules for nose-to-brain delivery: preclinical evaluation in glioblastoma.
Fraga Dias A, Dallemole DR, Bruinsmann FA, Lopes Silva LF, Cruz-López O, Conejo-García A, Oliveira Battastini AM, Campos JM, Guterres SS, Pohlmann AR, Figueiró F. Fraga Dias A, et al. Among authors: campos jm. Nanomedicine (Lond). 2021 Oct;16(23):2095-2115. doi: 10.2217/nnm-2021-0164. Epub 2021 Sep 15. Nanomedicine (Lond). 2021. PMID: 34523353
New insights into cytotoxic mechanisms of bozepinib against glioblastoma.
Dias AF, Scholl JN, Moritz CEJ, Kagami LP, das Neves GM, Eifler-Lima VL, Cruz-López O, Conejo-García A, Sévigny J, Battastini AMO, Campos JM, Figueiró F. Dias AF, et al. Among authors: campos jm. Eur J Pharm Sci. 2021 Jul 1;162:105823. doi: 10.1016/j.ejps.2021.105823. Epub 2021 Mar 27. Eur J Pharm Sci. 2021. PMID: 33781855
Bozepinib, a novel small antitumor agent, induces PKR-mediated apoptosis and synergizes with IFNα triggering apoptosis, autophagy and senescence.
Marchal JA, Carrasco E, Ramirez A, Jiménez G, Olmedo C, Peran M, Agil A, Conejo-García A, Cruz-López O, Campos JM, García MÁ. Marchal JA, et al. Among authors: campos jm. Drug Des Devel Ther. 2013 Oct 29;7:1301-13. doi: 10.2147/DDDT.S51354. eCollection 2013. Drug Des Devel Ther. 2013. PMID: 24194639 Free PMC article.