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Tubulin Resists Degradation by Cereblon-Recruiting PROTACs.
Gasic I, Groendyke BJ, Nowak RP, Yuan JC, Kalabathula J, Fischer ES, Gray NS, Mitchison TJ. Gasic I, et al. Among authors: kalabathula j. Cells. 2020 Apr 27;9(5):1083. doi: 10.3390/cells9051083. Cells. 2020. PMID: 32349222 Free PMC article.
A biphenyl inhibitor of eIF4E targeting an internal binding site enables the design of cell-permeable PROTAC-degraders.
Fischer PD, Papadopoulos E, Dempersmier JM, Wang ZF, Nowak RP, Donovan KA, Kalabathula J, Gorgulla C, Junghanns PPM, Kabha E, Dimitrakakis N, Petrov OI, Mitsiades C, Ducho C, Gelev V, Fischer ES, Wagner G, Arthanari H. Fischer PD, et al. Among authors: kalabathula j. Eur J Med Chem. 2021 Jul 5;219:113435. doi: 10.1016/j.ejmech.2021.113435. Epub 2021 Apr 8. Eur J Med Chem. 2021. PMID: 33892272 Free PMC article.