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2019 3
2020 5
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2023 1
2024 0

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PROTAC antibiotics: the time is now.
Sarathy JP, Aldrich CC, Go ML, Dick T. Sarathy JP, et al. Expert Opin Drug Discov. 2023 Apr;18(4):363-370. doi: 10.1080/17460441.2023.2178413. Epub 2023 Feb 21. Expert Opin Drug Discov. 2023. PMID: 37027333 Free PMC article.
Pyrazinamide triggers degradation of its target aspartate decarboxylase.
Gopal P, Sarathy JP, Yee M, Ragunathan P, Shin J, Bhushan S, Zhu J, Akopian T, Kandror O, Lim TK, Gengenbacher M, Lin Q, Rubin EJ, Grüber G, Dick T. Gopal P, et al. Among authors: sarathy jp. Nat Commun. 2020 Apr 3;11(1):1661. doi: 10.1038/s41467-020-15516-1. Nat Commun. 2020. PMID: 32245967 Free PMC article.
Discovery of a Novel Mycobacterial F-ATP Synthase Inhibitor and its Potency in Combination with Diarylquinolines.
Hotra A, Ragunathan P, Ng PS, Seankongsuk P, Harikishore A, Sarathy JP, Saw WG, Lakshmanan U, Sae-Lao P, Kalia NP, Shin J, Kalyanasundaram R, Anbarasu S, Parthasarathy K, Pradeep CN, Makhija H, Dröge P, Poulsen A, Tan JHL, Pethe K, Dick T, Bates RW, Grüber G. Hotra A, et al. Among authors: sarathy jp. Angew Chem Int Ed Engl. 2020 Aug 3;59(32):13295-13304. doi: 10.1002/anie.202002546. Epub 2020 May 26. Angew Chem Int Ed Engl. 2020. PMID: 32337801
11 results