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Sildenafil reduces bisphosphonate-induced jaw osteonecrosis in rats.
Mroczek T, Delfrate G, Mecca LEA, Andreis JD, Lipinski LC, Fernandes D, da Campos Soriani Azevedo M, Melchiades JL, Garlet GP, Franco GCN, Claudino M. Mroczek T, et al. Among authors: melchiades jl. Clin Oral Investig. 2023 May;27(5):2437-2448. doi: 10.1007/s00784-023-04890-x. Epub 2023 Feb 11. Clin Oral Investig. 2023. PMID: 36764974 No abstract available.
FTY720 administration results in a M2 associated immunoregulatory effect that positively influences the outcome of alveolar bone repair outcome in mice.
Tabanez AP, de Campos Soriani Azevedo M, Melchiades JL, Fonseca AC, Francisconi CF, Colavite PM, Biguetti CC, de Oliveira Rodini Pegoraro C, Trombone APF, Garlet GP. Tabanez AP, et al. Among authors: melchiades jl. Bone. 2022 Oct;163:116506. doi: 10.1016/j.bone.2022.116506. Epub 2022 Jul 25. Bone. 2022. PMID: 35902072
Microtomographic, histomorphometric, and molecular features show a normal alveolar bone healing process in iNOS-deficient mice along a compensatory upregulation of eNOS and nNOS isoforms.
Francisconi CF, Colavite PM, Fonseca AC, Azevedo MCS, Tabanez AP, Melchiades JL, Vieira AE, Repeke CEP, Claudino M, Garlet GP. Francisconi CF, et al. Among authors: melchiades jl. J Appl Oral Sci. 2023 Mar 20;31:e20220436. doi: 10.1590/1678-7757-2022-0436. eCollection 2023. J Appl Oral Sci. 2023. PMID: 36946828 Free PMC article.
Macrophage Polarization and Alveolar Bone Healing Outcome: Despite a Significant M2 Polarizing Effect, VIP and PACAP Treatments Present a Minor Impact in Alveolar Bone Healing in Homeostatic Conditions.
Azevedo MCS, Fonseca AC, Colavite PM, Melchiades JL, Tabanez AP, Codo AC, de Medeiros AI, Trombone APF, Garlet GP. Azevedo MCS, et al. Among authors: melchiades jl. Front Immunol. 2021 Dec 21;12:782566. doi: 10.3389/fimmu.2021.782566. eCollection 2021. Front Immunol. 2021. PMID: 34992601 Free PMC article.
Vasoactive Intestinal Peptide Immunoregulatory Role at the Periapex: Associative and Mechanistic Evidences from Human and Experimental Periapical Lesions.
de Campos Soriani Azevedo M, Garlet TP, Francisconi CF, Colavite PM, Tabanez AP, Melchiades JL, Favaro Trombone AP, Sfeir C, Little S, Silva RM, Garlet GP. de Campos Soriani Azevedo M, et al. Among authors: melchiades jl. J Endod. 2019 Oct;45(10):1228-1236. doi: 10.1016/j.joen.2019.06.013. Epub 2019 Aug 8. J Endod. 2019. PMID: 31402064