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Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease.
Salloway S, Sperling R, Fox NC, Blennow K, Klunk W, Raskind M, Sabbagh M, Honig LS, Porsteinsson AP, Ferris S, Reichert M, Ketter N, Nejadnik B, Guenzler V, Miloslavsky M, Wang D, Lu Y, Lull J, Tudor IC, Liu E, Grundman M, Yuen E, Black R, Brashear HR; Bapineuzumab 301 and 302 Clinical Trial Investigators. Salloway S, et al. N Engl J Med. 2014 Jan 23;370(4):322-33. doi: 10.1056/NEJMoa1304839. N Engl J Med. 2014. PMID: 24450891 Free PMC article. Clinical Trial.
At week 78, the between-group differences in the change from baseline in the ADAS-cog11 and DAD scores (bapineuzumab group minus placebo group) were -0.2 (P=0.80) and -1.2 (P=0.34), respectively, in the carrier study; the corresponding differences in the noncarrier …
At week 78, the between-group differences in the change from baseline in the ADAS-cog11 and DAD scores (bapineuzumab group minus placebo gro …
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.
Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM, Ahumada-Castro U, Aits S, Aizawa S, Akkoc Y, Akoumianaki T, Akpinar HA, Al-Abd AM, Al-Akra L, Al-Gharaibeh A, Alaoui-Jamali MA, Alberti S, Alcocer-Gómez E, Alessandri C, Ali M, Alim Al-Bari MA, Aliwaini S, Alizadeh J, Almacellas E, Almasan A, Alonso A, Alonso GD, Altan-Bonnet N, Altieri DC, Álvarez ÉMC, Alves S, Alves da Costa C, Alzaharna MM, Amadio M, Amantini C, Amaral C, Ambrosio S, Amer AO, Ammanathan V, An Z, Andersen SU, Andrabi SA, Andrade-Silva M, Andres AM, Angelini S, Ann D, Anozie UC, Ansari MY, Antas P, Antebi A, Antón Z, Anwar T, Apetoh L, Apostolova N, Araki T, Araki Y, Arasaki K, Araújo WL, Araya J, Arden C, Arévalo MA, Arguelles S, Arias E, Arikkath J, Arimoto H, Ariosa AR, Armstrong-James D, Arnauné-Pelloquin L, Aroca A, Arroyo DS, Arsov I, Artero R, Asaro DML, Aschner M, Ashrafizadeh M, Ashur-Fabian O, Atanasov AG, Au AK, Auberger P, Auner HW, Aurelian L, Autelli R… See abstract for full author list ➔ Klionsky DJ, et al. Autophagy. 2021 Jan;17(1):1-382. doi: 10.1080/15548627.2020.1797280. Epub 2021 Feb 8. Autophagy. 2021. PMID: 33634751 Free PMC article.
Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with mild cognitive impairment.
McCleery J, Abraham RP, Denton DA, Rutjes AW, Chong LY, Al-Assaf AS, Griffith DJ, Rafeeq S, Yaman H, Malik MA, Di Nisio M, Martínez G, Vernooij RW, Tabet N. McCleery J, et al. Cochrane Database Syst Rev. 2018 Nov 1;11(11):CD011905. doi: 10.1002/14651858.CD011905.pub2. Cochrane Database Syst Rev. 2018. PMID: 30383288 Free PMC article.
Death following pulmonary complications of surgery before and during the SARS-CoV-2 pandemic.
STARSurg Collaborative and COVIDSurg Collaborative. STARSurg Collaborative and COVIDSurg Collaborative. Br J Surg. 2021 Dec 1;108(12):1448-1464. doi: 10.1093/bjs/znab336. Br J Surg. 2021. PMID: 34871379 Free PMC article.

The pulmonary complication rate was similar (7.1 per cent (216 of 3031) versus 6.3 per cent (274 of 4371); P = 0.158) but the mortality rate was significantly higher (0.7 per cent (20 of 3031) versus 2.0 per cent (87 of 4371); P < 0.001) among patients who had su

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The pulmonary complication rate was similar (7.1 per cent (216 of 3031) versus 6.3 per cent (274 of 4371); P = 0.158) but the mortali …
Alternatives in Donkey semen cryopreservation: Mare vs. Jenny Colostrum.
Álvarez C, González N, Luño V, Martínez F, Gil L. Álvarez C, et al. Reprod Domest Anim. 2019 Oct;54 Suppl 4:94-97. doi: 10.1111/rda.13516. Reprod Domest Anim. 2019. PMID: 31625242
The aim of this study was to test and compare two new components in extenders for freezing donkey semen: mare colostrum and jenny colostrum. Colostrum was obtained from four mares and four jennies right after the foal's birth. ...In conclusion, the extender containing j …
The aim of this study was to test and compare two new components in extenders for freezing donkey semen: mare colostrum and jenny col …
Identifying structure-absorption relationships and predicting absorption strength of non-fullerene acceptors for organic photovoltaics.
Yan J, Rodríguez-Martínez X, Pearce D, Douglas H, Bili D, Azzouzi M, Eisner F, Virbule A, Rezasoltani E, Belova V, Dörling B, Few S, Szumska AA, Hou X, Zhang G, Yip HL, Campoy-Quiles M, Nelson J. Yan J, et al. Energy Environ Sci. 2022 May 20;15(7):2958-2973. doi: 10.1039/d2ee00887d. eCollection 2022 Jul 13. Energy Environ Sci. 2022. PMID: 35923416 Free PMC article.
Forming new health behavior habits during weight loss maintenance-The PREVIEW study.
Huttunen-Lenz M, Hansen S, Raben A, Westerterp-Plantenga M, Macdonald I, Stratton G, Swindell N, Martinez JA, Handjieva-Darlenska T, Poppitt SD, Silvestre MP, Fogelholm M, Jalo E, Brand-Miller J, Muirhead R, Larsen TM, Vestentoft PS, Handjiev S, Schlicht W. Huttunen-Lenz M, et al. Health Psychol. 2022 Aug;41(8):549-558. doi: 10.1037/hea0001182. Epub 2022 Jul 4. Health Psychol. 2022. PMID: 35787141 Clinical Trial.
Higher habit strength for energy-dense diet was significantly associated with larger weight regain (p .007). No changes in motivation or interactions with PREMIT attendance were observed. ...
Higher habit strength for energy-dense diet was significantly associated with larger weight regain (p .007). No changes in motivation …
Long-Term Follow-Up of a Lifestyle Intervention for Late-Midlife, Rural-Dwelling Latinos in Primary Care.
Schepens Niemiec SL, Vigen CLP, Martínez J, Blanchard J, Carlson M. Schepens Niemiec SL, et al. Am J Occup Ther. 2021 Mar-Apr;75(2):7502205020p1-7502205020p11. doi: 10.5014/ajot.2021.042861. Am J Occup Ther. 2021. PMID: 33657344 Free PMC article.
RESULTS: Participants (N = 27) demonstrated clinically significant pretreatment to long-term follow-up benefits in all symptom-well-being dimensions (Cohen's d 0.8, p .004), with additional gains from posttreatment to long-term follow-up (d 0.4, p .05). ...
RESULTS: Participants (N = 27) demonstrated clinically significant pretreatment to long-term follow-up benefits in all symptom-well-being di …
Association between antral follicle count and reproductive measures in New Zealand lactating dairy cows maintained in a pasture-based production system.
Martinez MF, Sanderson N, Quirke LD, Lawrence SB, Juengel JL. Martinez MF, et al. Theriogenology. 2016 Feb;85(3):466-75. doi: 10.1016/j.theriogenology.2015.09.026. Epub 2015 Sep 25. Theriogenology. 2016. PMID: 26489910

The AFC was positively associated (P < 0.0001) with age. Progesterone concentrations during diestrus were greater (P < 0.05) in high-AFC cows (7.6 0.3 ng/mL) than in low-AFC cows (6.5 0.3 ng/mL), whether these were pregnant (7.7 0.3 ng/mL) or not (6.3 0.2 ng/m

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The AFC was positively associated (P < 0.0001) with age. Progesterone concentrations during diestrus were greater (P < 0

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Surgical Wound Complications after Colorectal Surgery with Single-Use Negative-Pressure Wound Therapy Versus Surgical Dressing over Closed Incisions: A Randomized Controlled Trial.
León Arellano M, Barragán Serrano C, Guedea M, Garcia Pérez JC, Sanz Ortega G, Guevara-Martinez J, Gomez Abril S, González Puga C, Arroyo A, Cantero Cid R. León Arellano M, et al. Adv Skin Wound Care. 2021 Dec 1;34(12):657-661. doi: 10.1097/01.ASW.0000756512.87211.13. Adv Skin Wound Care. 2021. PMID: 34175866 Clinical Trial.
On day 15, the SSI rate was 12/75 (16.0%) in the ciNPT group versus 21/73 (28.8%) in the control group; however, this difference was only marginally statistically significant (P = .0621). At 1 month, the SSI rate remained lower in the ciNPT group (13/75 [17.3%] vs 21/73 [2 …
On day 15, the SSI rate was 12/75 (16.0%) in the ciNPT group versus 21/73 (28.8%) in the control group; however, this difference was only ma …
18 results