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Brain pharmacokinetics of ganciclovir in rats with orthotopic BT4C glioma.
Gynther M, Kääriäinen TM, Hakkarainen JJ, Jalkanen AJ, Petsalo A, Lehtonen M, Peura L, Kurkipuro J, Samaranayake H, Ylä-Herttuala S, Rautio J, Forsberg MM. Gynther M, et al. Among authors: hakkarainen jj. Drug Metab Dispos. 2015 Jan;43(1):140-6. doi: 10.1124/dmd.114.059840. Epub 2014 Oct 27. Drug Metab Dispos. 2015. PMID: 25349125
Poly(lactic-co-glycolic acid) Nanoparticles Encapsulating the Prenylated Flavonoid, Xanthohumol, Protect Corneal Epithelial Cells from Dry Eye Disease-Associated Oxidative Stress.
Ghosh AK, Thapa R, Hariani HN, Volyanyuk M, Ogle SD, Orloff KA, Ankireddy S, Lai K, Žiniauskaitė A, Stubbs EB Jr, Kalesnykas G, Hakkarainen JJ, Langert KA, Kaja S. Ghosh AK, et al. Pharmaceutics. 2021 Aug 30;13(9):1362. doi: 10.3390/pharmaceutics13091362. Pharmaceutics. 2021. PMID: 34575438 Free PMC article.
Manganese(III) tetrakis(1-methyl-4-pyridyl) porphyrin, a superoxide dismutase mimetic, reduces disease severity in in vitro and in vivo models for dry-eye disease.
Žiniauskaitė A, Ragauskas S, Ghosh AK, Thapa R, Roessler AE, Koulen P, Kalesnykas G, Hakkarainen JJ, Kaja S. Žiniauskaitė A, et al. Among authors: hakkarainen jj. Ocul Surf. 2019 Apr;17(2):257-264. doi: 10.1016/j.jtos.2019.02.006. Epub 2019 Feb 23. Ocul Surf. 2019. PMID: 30807830 Free PMC article.
Comparison of in vitro cell models in predicting in vivo brain entry of drugs.
Hakkarainen JJ, Jalkanen AJ, Kääriäinen TM, Keski-Rahkonen P, Venäläinen T, Hokkanen J, Mönkkönen J, Suhonen M, Forsberg MM. Hakkarainen JJ, et al. Int J Pharm. 2010 Dec 15;402(1-2):27-36. doi: 10.1016/j.ijpharm.2010.09.016. Epub 2010 Oct 8. Int J Pharm. 2010. PMID: 20920560
13 results