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2002 1
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Page 1
4-Alkyl-1,2,4-triazole-3-thione analogues as metallo-β-lactamase inhibitors.
Gavara L, Legru A, Verdirosa F, Sevaille L, Nauton L, Corsica G, Mercuri PS, Sannio F, Feller G, Coulon R, De Luca F, Cerboni G, Tanfoni S, Chelini G, Galleni M, Docquier JD, Hernandez JF. Gavara L, et al. Among authors: hernandez jf. Bioorg Chem. 2021 Aug;113:105024. doi: 10.1016/j.bioorg.2021.105024. Epub 2021 May 26. Bioorg Chem. 2021. PMID: 34116340
4-Amino-1,2,4-triazole-3-thione-derived Schiff bases as metallo-β-lactamase inhibitors.
Gavara L, Sevaille L, De Luca F, Mercuri P, Bebrone C, Feller G, Legru A, Cerboni G, Tanfoni S, Baud D, Cutolo G, Bestgen B, Chelini G, Verdirosa F, Sannio F, Pozzi C, Benvenuti M, Kwapien K, Fischer M, Becker K, Frère JM, Mangani S, Gresh N, Berthomieu D, Galleni M, Docquier JD, Hernandez JF. Gavara L, et al. Among authors: hernandez jf. Eur J Med Chem. 2020 Dec 15;208:112720. doi: 10.1016/j.ejmech.2020.112720. Epub 2020 Aug 20. Eur J Med Chem. 2020. PMID: 32937203
Squash inhibitors: from structural motifs to macrocyclic knottins.
Chiche L, Heitz A, Gelly JC, Gracy J, Chau PT, Ha PT, Hernandez JF, Le-Nguyen D. Chiche L, et al. Among authors: hernandez jf. Curr Protein Pept Sci. 2004 Oct;5(5):341-349. doi: 10.2174/1389203043379477. Curr Protein Pept Sci. 2004. PMID: 15551519 Review.
1,2,4-Triazole-3-thione Compounds as Inhibitors of Dizinc Metallo-β-lactamases.
Sevaille L, Gavara L, Bebrone C, De Luca F, Nauton L, Achard M, Mercuri P, Tanfoni S, Borgianni L, Guyon C, Lonjon P, Turan-Zitouni G, Dzieciolowski J, Becker K, Bénard L, Condon C, Maillard L, Martinez J, Frère JM, Dideberg O, Galleni M, Docquier JD, Hernandez JF. Sevaille L, et al. Among authors: hernandez jf. ChemMedChem. 2017 Jun 21;12(12):972-985. doi: 10.1002/cmdc.201700186. Epub 2017 Jun 12. ChemMedChem. 2017. PMID: 28505394 Free article.
1,2,4-Triazole-3-thione analogues with an arylakyl group at position 4 as metallo-β-lactamase inhibitors.
Gavara L, Verdirosa F, Sevaille L, Legru A, Corsica G, Nauton L, Sandra Mercuri P, Sannio F, De Luca F, Hadjadj M, Cerboni G, Vo Hoang Y, Licznar-Fajardo P, Galleni M, Docquier JD, Hernandez JF. Gavara L, et al. Among authors: hernandez jf. Bioorg Med Chem. 2022 Oct 15;72:116964. doi: 10.1016/j.bmc.2022.116964. Epub 2022 Aug 11. Bioorg Med Chem. 2022. PMID: 36030663 Free article.
1,2,4-Triazole-3-Thione Analogues with a 2-Ethylbenzoic Acid at Position 4 as VIM-type Metallo-β-Lactamase Inhibitors.
Verdirosa F, Gavara L, Sevaille L, Tassone G, Corsica G, Legru A, Feller G, Chelini G, Mercuri PS, Tanfoni S, Sannio F, Benvenuti M, Cerboni G, De Luca F, Bouajila E, Vo Hoang Y, Licznar-Fajardo P, Galleni M, Pozzi C, Mangani S, Docquier JD, Hernandez JF. Verdirosa F, et al. Among authors: hernandez jf. ChemMedChem. 2022 Apr 5;17(7):e202100699. doi: 10.1002/cmdc.202100699. Epub 2022 Feb 4. ChemMedChem. 2022. PMID: 35050549
Optimization of 1,2,4-Triazole-3-thiones toward Broad-Spectrum Metallo-β-lactamase Inhibitors Showing Potent Synergistic Activity on VIM- and NDM-1-Producing Clinical Isolates.
Legru A, Verdirosa F, Vo-Hoang Y, Tassone G, Vascon F, Thomas CA, Sannio F, Corsica G, Benvenuti M, Feller G, Coulon R, Marcoccia F, Devente SR, Bouajila E, Piveteau C, Leroux F, Deprez-Poulain R, Deprez B, Licznar-Fajardo P, Crowder MW, Cendron L, Pozzi C, Mangani S, Docquier JD, Hernandez JF, Gavara L. Legru A, et al. Among authors: hernandez jf. J Med Chem. 2022 Dec 22;65(24):16392-16419. doi: 10.1021/acs.jmedchem.2c01257. Epub 2022 Nov 30. J Med Chem. 2022. PMID: 36450011 Free article.
JLK inhibitors: isocoumarin compounds as putative probes to selectively target the gamma-secretase pathway.
Checler F, Alves da Costa C, Ayral E, Andrau D, Dumanchin C, Farzan M, Hernandez JF, Martinez J, Lefranc-Jullien S, Marambaud P, Pasini A, Petit A, Phiel C, Robert P, St George-Hyslop P, Wilk S. Checler F, et al. Among authors: hernandez jf. Curr Alzheimer Res. 2005 Jul;2(3):327-34. doi: 10.2174/1567205054367874. Curr Alzheimer Res. 2005. PMID: 15974898 Review.
53 results