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A combination of two resistance mechanisms is critical for tick-borne encephalitis virus escape from a broadly neutralizing human antibody.
Svoboda P, Haviernik J, Bednar P, Matkovic M, Cervantes Rincón T, Keeffe J, Palus M, Salat J, Agudelo M, Nussenzweig MC, Cavalli A, Robbiani DF, Ruzek D. Svoboda P, et al. Among authors: haviernik j. Cell Rep. 2023 Sep 26;42(9):113149. doi: 10.1016/j.celrep.2023.113149. Epub 2023 Sep 19. Cell Rep. 2023. PMID: 37715951 Free PMC article.
Broad-Spectrum Antiviral Activity of 3'-Deoxy-3'-Fluoroadenosine against Emerging Flaviviruses.
Eyer L, Svoboda P, Balvan J, Vičar T, Raudenská M, Štefánik M, Haviernik J, Huvarová I, Straková P, Rudolf I, Hubálek Z, Seley-Radtke K, de Clercq E, Růžek D. Eyer L, et al. Among authors: haviernik j. Antimicrob Agents Chemother. 2021 Jan 20;65(2):e01522-20. doi: 10.1128/AAC.01522-20. Print 2021 Jan 20. Antimicrob Agents Chemother. 2021. PMID: 33229424 Free PMC article.
Bispecific IgG neutralizes SARS-CoV-2 variants and prevents escape in mice.
De Gasparo R, Pedotti M, Simonelli L, Nickl P, Muecksch F, Cassaniti I, Percivalle E, Lorenzi JCC, Mazzola F, Magrì D, Michalcikova T, Haviernik J, Honig V, Mrazkova B, Polakova N, Fortova A, Tureckova J, Iatsiuk V, Di Girolamo S, Palus M, Zudova D, Bednar P, Bukova I, Bianchini F, Mehn D, Nencka R, Strakova P, Pavlis O, Rozman J, Gioria S, Sammartino JC, Giardina F, Gaiarsa S, Pan-Hammarström Q, Barnes CO, Bjorkman PJ, Calzolai L, Piralla A, Baldanti F, Nussenzweig MC, Bieniasz PD, Hatziioannou T, Prochazka J, Sedlacek R, Robbiani DF, Ruzek D, Varani L. De Gasparo R, et al. Among authors: haviernik j. Nature. 2021 May;593(7859):424-428. doi: 10.1038/s41586-021-03461-y. Epub 2021 Mar 25. Nature. 2021. PMID: 33767445
Bispecific antibody neutralizes circulating SARS-CoV-2 variants, prevents escape and protects mice from disease.
De Gasparo R, Pedotti M, Simonelli L, Nickl P, Muecksch F, Cassaniti I, Percivalle E, Lorenzi JCC, Mazzola F, Magrì D, Michalcikova T, Haviernik J, Honig V, Mrazkova B, Polakova N, Fortova A, Tureckova J, Iatsiuk V, Girolamo SD, Palus M, Zudova D, Bednar P, Bukova I, Bianchini F, Mehn D, Nencka R, Strakova P, Pavlis O, Rozman J, Gioria S, Camilla Sammartino J, Giardina F, Gaiarsa S, Hammarström QP, Barnes CO, Bjorkman PJ, Calzolai L, Piralla A, Baldanti F, Nussenzweig MC, Bieniasz PD, Hatziioannou T, Prochazka J, Sedlacek R, Robbiani DF, Ruzek D, Varani L. De Gasparo R, et al. Among authors: haviernik j. bioRxiv [Preprint]. 2021 Mar 5:2021.01.22.427567. doi: 10.1101/2021.01.22.427567. bioRxiv. 2021. PMID: 33501434 Free PMC article. Preprint.
Guanine quadruplexes in the RNA genome of the tick-borne encephalitis virus: their role as a new antiviral target and in virus biology.
Holoubek J, Bednářová K, Haviernik J, Huvarová I, Dvořáková Z, Černý J, Outlá M, Salát J, Konkol'ová E, Boura E, Růžek D, Vorlíčková M, Eyer L, Renčiuk D. Holoubek J, et al. Among authors: haviernik j. Nucleic Acids Res. 2022 May 6;50(8):4574-4600. doi: 10.1093/nar/gkac225. Nucleic Acids Res. 2022. PMID: 35420134 Free PMC article.
Publisher Correction: Bispecific IgG neutralizes SARS-CoV-2 variants and prevents escape in mice.
De Gasparo R, Pedotti M, Simonelli L, Nickl P, Muecksch F, Cassaniti I, Percivalle E, Lorenzi JCC, Mazzola F, Magrì D, Michalcikova T, Haviernik J, Honig V, Mrazkova B, Polakova N, Fortova A, Tureckova J, Iatsiuk V, Di Girolamo S, Palus M, Zudova D, Bednar P, Bukova I, Bianchini F, Mehn D, Nencka R, Strakova P, Pavlis O, Rozman J, Gioria S, Sammartino JC, Giardina F, Gaiarsa S, Pan-Hammarström Q, Barnes CO, Bjorkman PJ, Calzolai L, Piralla A, Baldanti F, Nussenzweig MC, Bieniasz PD, Hatziioannou T, Prochazka J, Sedlacek R, Robbiani DF, Ruzek D, Varani L. De Gasparo R, et al. Among authors: haviernik j. Nature. 2021 Sep;597(7874):E2. doi: 10.1038/s41586-021-03719-5. Nature. 2021. PMID: 34345019 Free PMC article. No abstract available.
18 results