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Cryo-EM structures of Trypanosoma brucei gambiense ISG65 with human complement C3 and C3b and their roles in alternative pathway restriction.
Nat Commun. 2023 Apr 27;14(1):2403. doi: 10.1038/s41467-023-37988-7.
Nat Commun. 2023.
PMID: 37105991
Free PMC article.
The role of invariant surface glycoprotein 75 in xenobiotic acquisition by African trypanosomes.
Makarov A, Began J, Mautone IC, Pinto E, Ferguson L, Zoltner M, Zoll S, Field MC.
Makarov A, et al. Among authors: began j.
Microb Cell. 2023 Jan 27;10(2):18-35. doi: 10.15698/mic2023.02.790. eCollection 2023 Feb 6.
Microb Cell. 2023.
PMID: 36789350
Free PMC article.
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Sensitive Versatile Fluorogenic Transmembrane Peptide Substrates for Rhomboid Intramembrane Proteases.
Tichá A, Stanchev S, Škerle J, Began J, Ingr M, Švehlová K, Polovinkin L, Růžička M, Bednárová L, Hadravová R, Poláchová E, Rampírová P, Březinová J, Kašička V, Majer P, Strisovsky K.
Tichá A, et al. Among authors: began j.
J Biol Chem. 2017 Feb 17;292(7):2703-2713. doi: 10.1074/jbc.M116.762849. Epub 2017 Jan 9.
J Biol Chem. 2017.
PMID: 28069810
Free PMC article.
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Rhomboid intramembrane protease YqgP licenses bacterial membrane protein quality control as adaptor of FtsH AAA protease.
Began J, Cordier B, Březinová J, Delisle J, Hexnerová R, Srb P, Rampírová P, Kožíšek M, Baudet M, Couté Y, Galinier A, Veverka V, Doan T, Strisovsky K.
Began J, et al.
EMBO J. 2020 May 18;39(10):e102935. doi: 10.15252/embj.2019102935. Epub 2020 Jan 13.
EMBO J. 2020.
PMID: 31930742
Free PMC article.
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General and Modular Strategy for Designing Potent, Selective, and Pharmacologically Compliant Inhibitors of Rhomboid Proteases.
Tichá A, Stanchev S, Vinothkumar KR, Mikles DC, Pachl P, Began J, Škerle J, Švehlová K, Nguyen MTN, Verhelst SHL, Johnson DC, Bachovchin DA, Lepšík M, Majer P, Strisovsky K.
Tichá A, et al. Among authors: began j.
Cell Chem Biol. 2017 Dec 21;24(12):1523-1536.e4. doi: 10.1016/j.chembiol.2017.09.007. Epub 2017 Oct 26.
Cell Chem Biol. 2017.
PMID: 29107700
Free PMC article.
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The History of Anti-Trypanosome Vaccine Development Shows That Highly Immunogenic and Exposed Pathogen-Derived Antigens Are Not Necessarily Good Target Candidates: Enolase and ISG75 as Examples.
Magez S, Li Z, Nguyen HTT, Pinto Torres JE, Van Wielendaele P, Radwanska M, Began J, Zoll S, Sterckx YG.
Magez S, et al. Among authors: began j.
Pathogens. 2021 Aug 19;10(8):1050. doi: 10.3390/pathogens10081050.
Pathogens. 2021.
PMID: 34451514
Free PMC article.
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Substrate binding and specificity of rhomboid intramembrane protease revealed by substrate-peptide complex structures.
Zoll S, Stanchev S, Began J, Skerle J, Lepšík M, Peclinovská L, Majer P, Strisovsky K.
Zoll S, et al. Among authors: began j.
EMBO J. 2014 Oct 16;33(20):2408-21. doi: 10.15252/embj.201489367. Epub 2014 Sep 12.
EMBO J. 2014.
PMID: 25216680
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