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Page 1
A comprehensive study of SARS-CoV-2 main protease (Mpro) inhibitor-resistant mutants selected in a VSV-based system.
bioRxiv [Preprint]. 2023 Oct 4:2023.09.22.558628. doi: 10.1101/2023.09.22.558628.
bioRxiv. 2023.
PMID: 37808638
Free PMC article.
Preprint.
Tracking mutation and drug-driven alterations of oncokinase conformations.
Feichtner A, Kugler V, Schwaighofer S, Nuener T, Fleischmann J, Stefan E.
Feichtner A, et al. Among authors: fleischmann j.
Memo. 2022 Jun;15(2):137-142. doi: 10.1007/s12254-021-00790-6. Epub 2022 Jan 21.
Memo. 2022.
PMID: 35677701
Free PMC article.
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Tracking and blocking interdependencies of cellular BRAF-MEK oncokinase activities.
Fleischmann J, Schwaighofer S, De Falco L, Enzler F, Feichtner A, Kugler V, Tschaikner P, Huber RG, Stefan E.
Fleischmann J, et al.
PNAS Nexus. 2023 Jun 5;2(6):pgad185. doi: 10.1093/pnasnexus/pgad185. eCollection 2023 Jun.
PNAS Nexus. 2023.
PMID: 37325027
Free PMC article.
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Mutation-oriented profiling of autoinhibitory kinase conformations predicts RAF inhibitor efficacies.
Mayrhofer JE, Enzler F, Feichtner A, Röck R, Fleischmann J, Raffeiner A, Tschaikner P, Ogris E, Huber RG, Hartl M, Schneider R, Troppmair J, Torres-Quesada O, Stefan E.
Mayrhofer JE, et al. Among authors: fleischmann j.
Proc Natl Acad Sci U S A. 2020 Dec 8;117(49):31105-31113. doi: 10.1073/pnas.2012150117. Epub 2020 Nov 23.
Proc Natl Acad Sci U S A. 2020.
PMID: 33229534
Free PMC article.
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Allosteric Kinase Inhibitors Reshape MEK1 Kinase Activity Conformations in Cells and In Silico.
Fleischmann J, Feichtner A, DeFalco L, Kugler V, Schwaighofer S, Huber RG, Stefan E.
Fleischmann J, et al.
Biomolecules. 2021 Mar 30;11(4):518. doi: 10.3390/biom11040518.
Biomolecules. 2021.
PMID: 33808483
Free PMC article.
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Enhanced TROSY Effect in [2-19 F, 2-13 C] Adenosine and ATP Analogs Facilitates NMR Spectroscopy of Very Large Biological RNAs in Solution.
Juen F, Glänzer D, Plangger R, Kugler V, Fleischmann J, Stefan E, Case DA, Kovacs H, Kwaku Dayie T, Kreutz C.
Juen F, et al. Among authors: fleischmann j.
Angew Chem Int Ed Engl. 2024 Feb 26;63(9):e202316273. doi: 10.1002/anie.202316273. Epub 2024 Jan 24.
Angew Chem Int Ed Engl. 2024.
PMID: 38185473
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