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Page 1
Showing results for haemin im
Search for Jaemin Im instead (1 results)
Human myeloid leukemia cell lines: a review.
Koeffler HP, Golde DW. Koeffler HP, et al. Blood. 1980 Sep;56(3):344-50. Blood. 1980. PMID: 6996765 Free article. Review.
The K562 line is composed of undifferentiated blast cells that are rich in glycophorin and may be induced to produce fetal and embryonic hemoglobin in the presence of hemin. The KG-1 cell line is composed predominantly of myeloblasts and promyelocytes. ...
The K562 line is composed of undifferentiated blast cells that are rich in glycophorin and may be induced to produce fetal and embryonic hem …
Nanoscale coordination polymers induce immunogenic cell death by amplifying radiation therapy mediated oxidative stress.
Huang Z, Wang Y, Yao D, Wu J, Hu Y, Yuan A. Huang Z, et al. Nat Commun. 2021 Jan 8;12(1):145. doi: 10.1038/s41467-020-20243-8. Nat Commun. 2021. PMID: 33420008 Free PMC article.
Here, we demonstrate a synergetic strategy for boosting radiation-induced immunogenic cell death by constructing gadolinium-hemin based nanoscale coordination polymers to simultaneously perform X-ray deposition and glutathione depletion. ...
Here, we demonstrate a synergetic strategy for boosting radiation-induced immunogenic cell death by constructing gadolinium-hemin bas …
Haemin deprivation renders Bacteroides fragilis hypersusceptible to metronidazole and cancels high-level metronidazole resistance.
Paunkov A, Gutenbrunner K, Sóki J, Leitsch D. Paunkov A, et al. J Antimicrob Chemother. 2022 Mar 31;77(4):1027-1031. doi: 10.1093/jac/dkab485. J Antimicrob Chemother. 2022. PMID: 35040989 Free PMC article.
We further tested whether haemin-deprived B. fragilis would be more susceptible to oxygen and oxidative stress. ...B. fragilis was incapable of scavenging oxygen when haemin was omitted. CONCLUSIONS: We propose that haemin deprivation overrules resistance mec …
We further tested whether haemin-deprived B. fragilis would be more susceptible to oxygen and oxidative stress. ...B. fragilis was in …
Kinetics and localisation of haemin-induced lipoprotein oxidation.
Morales NP, Chunephisal P, Janprasit J, Ishida Y, Luechapudiporn R, Yamada KI. Morales NP, et al. Free Radic Res. 2019 Oct;53(9-10):968-978. doi: 10.1080/10715762.2019.1660323. Epub 2019 Sep 20. Free Radic Res. 2019. PMID: 31452415
Haemin (iron (III)-protoporphyrin IX) is a degradation product of haemoglobin in circulating erythrocytes. Haemin may play a key oxidising agent for lipoprotein oxidation in patients with haemolytic anaemia. ...
Haemin (iron (III)-protoporphyrin IX) is a degradation product of haemoglobin in circulating erythrocytes. Haemin may play a k …
Update review of the acute porphyrias.
Stein PE, Badminton MN, Rees DC. Stein PE, et al. Br J Haematol. 2017 Feb;176(4):527-538. doi: 10.1111/bjh.14459. Epub 2016 Dec 16. Br J Haematol. 2017. PMID: 27982422 Free article. Review.
The diagnosis is made by finding increased porphobilinogen excretion in a light-protected random urine sample. Management includes administration of intravenous human haemin and supportive treatment with non-porphyrinogenic drugs. A few patients develop recurrent attacks, …
The diagnosis is made by finding increased porphobilinogen excretion in a light-protected random urine sample. Management includes administr …
Mechanisms of sickle cell alloimmunization.
Yazdanbakhsh K. Yazdanbakhsh K. Transfus Clin Biol. 2015 Aug;22(3):178-81. doi: 10.1016/j.tracli.2015.05.005. Epub 2015 Jun 6. Transfus Clin Biol. 2015. PMID: 26056038 Free PMC article. Review.
G-quadruplexes sense natural porphyrin metabolites for regulation of gene transcription and chromatin landscapes.
Li C, Yin Z, Xiao R, Huang B, Cui Y, Wang H, Xiang Y, Wang L, Lei L, Ye J, Li T, Zhong Y, Guo F, Xia Y, Fang P, Liang K. Li C, et al. Genome Biol. 2022 Dec 15;23(1):259. doi: 10.1186/s13059-022-02830-8. Genome Biol. 2022. PMID: 36522639 Free PMC article.
RESULTS: Based on the direct interaction between G4 and natural porphyrins, we establish genome-wide approaches to profile where the iron-liganded porphyrin hemin can bind in the chromatin. Hemin promotes genome-wide G4 formation, impairs transcription initiation, a …
RESULTS: Based on the direct interaction between G4 and natural porphyrins, we establish genome-wide approaches to profile where the iron-li …
Hemin treatment drives viral reactivation and plasma cell differentiation of EBV latently infected B cells.
Burnet AM, Brunetti T, Rochford R. Burnet AM, et al. PLoS Pathog. 2023 Aug 28;19(8):e1011561. doi: 10.1371/journal.ppat.1011561. eCollection 2023 Aug. PLoS Pathog. 2023. PMID: 37639483 Free PMC article.
Hemin treatment resulted in the expression of EBV immediate early, early and late lytic gene transcripts. ...To assess the transcriptional changes induced by hemin treatment, RNA sequencing was performed on mock- and hemin-treated Mutu I cells, and a shift fr …
Hemin treatment resulted in the expression of EBV immediate early, early and late lytic gene transcripts. ...To assess the transcript …
Antimicrobial properties of porphyrins.
Stojiljkovic I, Evavold BD, Kumar V. Stojiljkovic I, et al. Expert Opin Investig Drugs. 2001 Feb;10(2):309-20. doi: 10.1517/13543784.10.2.309. Expert Opin Investig Drugs. 2001. PMID: 11178343 Review.
The same uptake systems can be used to deliver antibiotic-porphyrin and antibacterial peptide-porphyrin conjugates. Haemin, the most well known natural porphyrin, possesses a significant antibacterial activity that is augmented by the presence of physiological concentratio …
The same uptake systems can be used to deliver antibiotic-porphyrin and antibacterial peptide-porphyrin conjugates. Haemin, the most …
COVID-19 and heme oxygenase: novel insight into the disease and potential therapies.
Hooper PL. Hooper PL. Cell Stress Chaperones. 2020 Sep;25(5):707-710. doi: 10.1007/s12192-020-01126-9. Epub 2020 Jun 4. Cell Stress Chaperones. 2020. PMID: 32500379 Free PMC article. Review.
Therapies with anti-viral properties that raise HO-1 include certain anesthetics (sevoflurane or isoflurane), hemin, estrogen, statins, curcumin, resveratrol, and melatonin. Controlled trials of these HO-1 inducers should be done in order to prevent or treat COVID-19 disea …
Therapies with anti-viral properties that raise HO-1 include certain anesthetics (sevoflurane or isoflurane), hemin, estrogen, statin …
457 results