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Combined Effect of Diosgenin Along with Ezetimibe or Atorvastatin on the Fate of Labelled Bile Acid and Cholesterol in Hypercholesterolemic Rats.
Marín-Medina A, Ruíz-Hidalgo G, Blé-Castillo JL, Zetina-Esquivel AM, Zamora RM, Juárez-Rojop IE, Díaz-Zagoya JC. Marín-Medina A, et al. Int J Environ Res Public Health. 2019 Feb 20;16(4):627. doi: 10.3390/ijerph16040627. Int J Environ Res Public Health. 2019. PMID: 30791676 Free PMC article.
We analyzed the effect of diosgenin, administered with atorvastatin or ezetimibe, on the fate of 3H(G)-taurocholic acid or 26-(14)C-cholesterol in hypercholesterolemic rats. Male Wistar rats received a hypercholesterolemic diet (HD), HD + atorvastatin (HD+ATV), HD + ezetim …
We analyzed the effect of diosgenin, administered with atorvastatin or ezetimibe, on the fate of 3H(G)-taurocholic acid or 26-(14)C-c …
Protective Action of Carica papaya on β-Cells in Streptozotocin-Induced Diabetic Rats.
Miranda-Osorio PH, Castell-Rodríguez AE, Vargas-Mancilla J, Tovilla-Zárate CA, Ble-Castillo JL, Aguilar-Domínguez DE, Juárez-Rojop IE, Díaz-Zagoya JC. Miranda-Osorio PH, et al. Int J Environ Res Public Health. 2016 Apr 27;13(5):446. doi: 10.3390/ijerph13050446. Int J Environ Res Public Health. 2016. PMID: 27128930 Free PMC article.
The aim of the present study was to investigate the effect of C. papaya L. leaf extract (CPLE) on pancreatic islets in streptozotocin (STZ)-induced diabetic rats, as well as on cultured normal pancreatic cells with STZ in the medium. ...
The aim of the present study was to investigate the effect of C. papaya L. leaf extract (CPLE) on pancreatic islets in streptozotocin …
Long-acting estrogenic responses of estradiol fatty acid esters.
Vazquez-Alcantara MA, Menjivar M, Garcia GA, Díaz-Zagoya JC, Garza-Flores J. Vazquez-Alcantara MA, et al. J Steroid Biochem. 1989 Dec;33(6):1111-8. doi: 10.1016/0022-4731(89)90417-2. J Steroid Biochem. 1989. PMID: 2515394
Estradiol esters at C-17 and C-3 with palmitic, stearic and oleic acids were chemically synthesized and then evaluated for their long-acting estrogenic responses in ovariectomized rats. ...The results disclosed that most of the estradiol derivatives evaluated exhibi …
Estradiol esters at C-17 and C-3 with palmitic, stearic and oleic acids were chemically synthesized and then evaluated for the …
Effects of the ethanolic extract of Spirulina maxima on endothelium dependent vasomotor responses of rat aortic rings.
Paredes-Carbajal MC, Torres-Durán PV, Díaz-Zagoya JC, Mascher D, Juárez-Oropeza MA. Paredes-Carbajal MC, et al. J Ethnopharmacol. 2001 Apr;75(1):37-44. doi: 10.1016/s0378-8741(00)00390-1. J Ethnopharmacol. 2001. PMID: 11282441
On rings with endothelium, the extract produced the following effects: (a) a concentration-dependent (60-1000 microg/ml) decrease of the contractile response to phenylephrine; (b) a rightward shift and a decrease in maximal developed tension, of the concentration--response curve …
On rings with endothelium, the extract produced the following effects: (a) a concentration-dependent (60-1000 microg/ml) decrease of the con …
Hypoglycemic action of Cucurbita ficifolia on Type 2 diabetic patients with moderately high blood glucose levels.
Acosta-Patiño JL, Jiménez-Balderas E, Juárez-Oropeza MA, Díaz-Zagoya JC. Acosta-Patiño JL, et al. J Ethnopharmacol. 2001 Sep;77(1):99-101. doi: 10.1016/s0378-8741(01)00272-0. J Ethnopharmacol. 2001. PMID: 11483384 Clinical Trial.
As expected, no significant changes on blood glucose were observed after giving the vehicle; however, the oral administration of C. ficifolia was followed by a significant decrease in blood glucose levels, from 12.07+/-1.69 mM (217.2+/-30.4 mg/dl) to 9.42+/-1.96 mM (169.6+ …
As expected, no significant changes on blood glucose were observed after giving the vehicle; however, the oral administration of C. f …