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Page 1
Dimethylcelecoxib inhibits prostaglandin E2 production.
Wobst I, Schiffmann S, Birod K, Maier TJ, Schmidt R, Angioni C, Geisslinger G, Grösch S. Wobst I, et al. Biochem Pharmacol. 2008 Jul 1;76(1):62-9. doi: 10.1016/j.bcp.2008.04.008. Epub 2008 Apr 24. Biochem Pharmacol. 2008. PMID: 18508034
The selective COX-2 inhibitor celecoxib modulates sphingolipid synthesis.
Schiffmann S, Sandner J, Schmidt R, Birod K, Wobst I, Schmidt H, Angioni C, Geisslinger G, Grösch S. Schiffmann S, et al. Among authors: wobst i. J Lipid Res. 2009 Jan;50(1):32-40. doi: 10.1194/jlr.M800122-JLR200. Epub 2008 Aug 18. J Lipid Res. 2009. PMID: 18711209 Free article.
The anti-proliferative potency of celecoxib is not a class effect of coxibs.
Schiffmann S, Maier TJ, Wobst I, Janssen A, Corban-Wilhelm H, Angioni C, Geisslinger G, Grösch S. Schiffmann S, et al. Among authors: wobst i. Biochem Pharmacol. 2008 Jul 15;76(2):179-87. doi: 10.1016/j.bcp.2008.04.017. Epub 2008 May 4. Biochem Pharmacol. 2008. PMID: 18547544
Ceramide synthases and ceramide levels are increased in breast cancer tissue.
Schiffmann S, Sandner J, Birod K, Wobst I, Angioni C, Ruckhäberle E, Kaufmann M, Ackermann H, Lötsch J, Schmidt H, Geisslinger G, Grösch S. Schiffmann S, et al. Among authors: wobst i. Carcinogenesis. 2009 May;30(5):745-52. doi: 10.1093/carcin/bgp061. Epub 2009 Mar 11. Carcinogenesis. 2009. PMID: 19279183
Cellular membranes function as a storage compartment for celecoxib.
Maier TJ, Schiffmann S, Wobst I, Birod K, Angioni C, Hoffmann M, Lopez JJ, Glaubitz C, Steinhilber D, Geisslinger G, Grösch S. Maier TJ, et al. Among authors: wobst i. J Mol Med (Berl). 2009 Oct;87(10):981-93. doi: 10.1007/s00109-009-0506-8. Epub 2009 Jul 30. J Mol Med (Berl). 2009. PMID: 19641861